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How to get fromChiasso to Sienaby train (Trenitalia), bus, car, train, or plane

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There are 6 ways to get from Chiasso to Siena by train (Trenitalia), bus, car, train, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Chiasso to Milano Centraletrain train S11
    2. Take the train from Milano Centrale to Firenze S.M.N.train train Fr
    3. Take the train from Firenze S.M.N. to Sienatrain train Re
    4h 56m
    €58–115

  2. Bus

    1. Take the bus from Como to Florence Villa Constanza Bus Stationbus bus
    2. Take the bus from Florence Villa Constanza Bus Station to Sienabus bus 1518 / ...
    6h 8m
    €66–95

  3. Drive  415.2 km

    1. Drive from Chiasso to Sienacar car 415.2 km
    4h 14m
    €75–108

  4. Train to Milano Malpensa Airport, fly, train

    1. Take the train from Mendrisio to Malpensa Aeroporto T1train train
    2. Fly from Milano Malpensa Airport (MXP) to Florence Peretola Airport (FLR)plane plane MXP - FLR
    3. Take the train from Firenze S.M.N. to Sienatrain train
    8h 3m
    €115–270

  5. Train, bus

    1. Take the train from Chiasso to Firenze S. M. N.train train Ec
    2. Take the bus from Firenze Autostazione to Siena-Via Tozzibus bus 131R / ...
    6h 5m
    €124–173

  6. Fly from Milan Linate Airport, train

    1. Fly from Milan Linate Airport (LIN) to Florence Peretola Airport (FLR)plane plane LIN - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain train
    7h 54m
    €129–257

Chiasso to Siena by train

Calendar128Weekly Trains
Duration4h 56mAverage Duration
Ticket€58Cheapest Price
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Comparing Your Travel Options

Map of how to get from Chiasso to Siena.ExpandLaunch map view
  • Distance: 448.2 km
  • Duration: 4h 56m

What companies run services between Chiasso, Switzerland and Siena, Italy?

You can take a train from Chiasso to Siena via Milano Centrale and Firenze S.M.N. in around 4h 56m. Alternatively, you can take a bus from Chiasso - Stazione to Siena via Como - Chiesa di San Zenone, Como, and Florence Villa Constanza Bus Station in around 6h 8m.

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