The average train between Milan and Siena takes 4h 53m and the fastest train takes 3h 42m. There is a train service every few hours from Milan to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Milan and Siena. The earliest departure is at 5:10 AM in the morning, and the last departure from Milan is at 9:20 PM which arrives into Siena at 7:55 AM. All services require a transfer, and take on average 4h 53m. The schedules shown below are for the next available departures.

4h 30m • 1 change

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4h 27m • 1 change

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4h 28m • 1 change

4h 27m • 1 change

4h 28m • 1 change

4h 30m • 1 change

3h 42m • 1 change

4h 27m • 1 change

4h 28m • 1 change

4h 30m • 1 change

3h 42m • 1 change

4h 27m • 1 change

4h 30m • 1 change

4h 30m • 1 change

4h 28m • 1 change
Want to know about travelling from Milan to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Siena. However, there are services departing from Milan station and arriving at Siena station via Firenze S.M.N.. The journey, including transfers, takes approximately 4h 53m.
Milan to Siena train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Siena train services, operated by Trenitalia Frecce, arrive at Siena station.
Book your Milan to Siena train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Milan and Siena is 293 km. The road distance is 397 km.
You can take a train from Milano Centrale to Siena via Firenze S.M.N. in around 4h 14m.