Brussels to Mendrisio trains

Travel from

Search accommodation with Expedia

Trip Overview

The average train between Brussels and Mendrisio takes 11h 44m and the fastest train takes 8h 40m. The train service runs several times per day from Brussels to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 44m
Duration: 1,117 km
Distance: CHF 314
Average price: 5 times a day
Frequency

Train via Paris

best

Take the train from Brussel-Zuid / Bruxelles-Midi to Paris Nordtrain
Take the train from Paris Gare De Lyon to Zuerich Hbtrain Tgv
Take the train from Zürich HB to Luganotrain Ec / ...

9h 25m

CHF 222–439

Brussels to Mendrisio train times

Trains run 5 times a day between Brussels and Mendrisio. The earliest departure is at 7:42 AM in the morning, and the last departure from Brussels is at 10:13 PM which arrives into Mendrisio at 1:57 PM. All services require a transfer at Paris Nord and take an average of 11h 44m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

3:42 PM → 8:57 AM
Arrives next day
17h 15m • 4 changes
9:16 PM → 1:57 PM
Arrives next day
16h 41m • 4 changes

Departing Friday, October 23, 2026

8:13 AM → 4:57 PM
8h 44m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes
3:42 PM → 8:57 AM
Arrives next day
17h 15m • 4 changes
Show more

Departing Saturday, October 24, 2026

8:13 AM → 4:57 PM
8h 44m • 4 changes
10:13 AM → 6:57 PM
8h 44m • 4 changes
12:13 PM → 8:57 PM
8h 44m • 4 changes
2:12 PM → 11:27 PM
9h 15m • 4 changes
Show more

Departing Sunday, October 25, 2026

10:13 AM → 6:57 PM
8h 44m • 4 changes
12:13 PM → 8:57 PM
8h 44m • 4 changes
2:12 PM → 10:57 PM
8h 45m • 4 changes
4:13 PM → 8:57 AM
Arrives next day
16h 44m • 4 changes
Show more

Departing Monday, October 26, 2026

7:42 AM → 4:57 PM
9h 15m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes
3:16 PM → 8:57 AM
Arrives next day
17h 41m • 4 changes
Show more

Departing Tuesday, October 27, 2026

7:42 AM → 4:57 PM
9h 15m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes
3:16 PM → 8:57 AM
Arrives next day
17h 41m • 4 changes
Show more

Departing Wednesday, October 28, 2026

7:42 AM → 4:57 PM
9h 15m • 4 changes
10:17 AM → 6:57 PM
8h 40m • 4 changes
1:13 PM → 11:27 PM
10h 14m • 4 changes

Frequently asked questions

Want to know about travelling from Brussels to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Brussels to Mendrisio.

Launch map view

Distance: 1,116.7 km
Duration: 11h 44m

What companies run services between Brussels, Belgium and Mendrisio, Switzerland?

You can take a train from Brussel-Zuid / Bruxelles-Midi to Mendrisio via Paris Nord, Paris Gare De Lyon, Zuerich Hb, Zürich HB, and Lugano in around 9h 25m.

Operators