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How to get fromWisconsin to St. Louisby plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus or train

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There are 9 ways to get from Wisconsin to St. Louis by plane, train (Amtrak), bus (Flixbus, Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)plane plane MKE - STL
    3h 30m
    $125–805

  2. Train (Amtrak)

    cheapest
    1. Take the train from Milwaukee to Chicago Union Stationtrain train Hiawatha Service / ...
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    7h 15m
    $52–168

  3. Bus

    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus Stationbus bus FlixBus 2548 / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus N2521 / ...
    9h 25m
    $55–112

  4. Drive 371.2 mi

    1. Drive from Milwaukee to St. Louiscar car 371.2 mi
    6h 16m
    $68–98

  5. Fly from Dane County Regional Airport-Truax Field

    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Lambert–St. Louis International Airport (STL)plane plane MSN - STL
    5h 48m
    $105–705

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    4h 56m
    $268–531

  7. Train to Chicago Midway International Airport, fly

    1. Take the train from Kenosha to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    5h 34m
    $97–616

  8. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomingtonbus bus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)plane plane MSP - STL
    5h 29m
    $143–744

  9. Bus, train

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus bus
    2. Take the bus from Multi-Modal Facility to Uptown Stationbus bus
    3. Take the train from Bloomington-Normal to St. Louistrain train
    10h 38m
    $100–166

Wisconsin to St. Louis by train (Amtrak)

Calendar38Weekly Trains
Duration7h 15mAverage Duration
Ticket$52Cheapest Price
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Questions & Answers

What companies run services between Wisconsin, USA and St. Louis, MO, USA?

Southwest Airlines and American Airlines fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL) 3 times a day. Alternatively, you can take a train from Milwaukee to St. Louis via Chicago Union Station in around 7h 15m.

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