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How to get fromWisconsin to St. Louisby plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus or train

Find Transport to St. Louis

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There are 9 ways to get from Wisconsin to St. Louis by plane, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from General Mitchell International Airport

    best
    1. Fly from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL)planeMKE - STL
    3h 30m
    $255–455

  2. Bus

    cheapest
    1. Take the bus from Milwaukee Intermodal Station to Chicago Bus StationbusGreyhound US0150S / ...
    2. Take the bus from Chicago Bus Station to St Louis Bus StationbusFlixBus N2521 / ...
    8h 55m
    $56–162

  3. Train (Amtrak)

    1. Take the train from Milwaukee to Chicago Union StationtrainHiawatha Service / ...
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    7h 15m
    $63–321

  4. Drive 371.2 mi

    1. Drive from Milwaukee to St. Louiscar371.2 mi
    6h 13m
    $68–98

  5. Fly from Dane County Regional Airport-Truax Field

    1. Fly from Dane County Regional Airport-Truax Field (MSN) to Lambert–St. Louis International Airport (STL)planeMSN - STL
    5h 36m
    $115–705

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 Departuresbus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)planeORD - STL
    4h 52m
    $208–541

  7. Train to Chicago Midway International Airport, fly

    1. Take the train from Kenosha to Chicago OTCtrain
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)planeMDW - STL
    5h 34m
    $84–565

  8. Bus to Minneapolis–Saint Paul International Airport, fly

    1. Take the bus from Eau Claire Amtrak Bus Stop to Mall of America - IKEA - Bloomingtonbus
    2. Fly from Minneapolis–Saint Paul International Airport (MSP) to Lambert–St. Louis International Airport (STL)planeMSP - STL
    5h 34m
    $291–691

  9. Bus, train

    1. Take the bus from Milwaukee Intermodal/Amtrak Station to O'Hare International Airport - Terminal 2 DeparturesbusWisconsin Coach Lines
    2. Take the train from Chicago Union Station to St. LouistrainLincoln Service / ...
    8h 32m
    $77–323

Wisconsin to St. Louis by train (Amtrak)

Calendar38Weekly Trains
Duration7h 15mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

What companies run services between Wisconsin, USA and St. Louis, MO, USA?

Southwest Airlines flies from General Mitchell International Airport (MKE) to Lambert–St. Louis International Airport (STL) twice daily. Alternatively, you can take a train from Milwaukee to St. Louis via Chicago Union Station in around 7h 15m.

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