The average bus between Wesley Chapel and Key Largo takes 17h 35m and the fastest bus takes 15h 55m. There is at least one bus per day from Wesley Chapel to Key Largo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Wesley Chapel and Key Largo. The earliest departure is at 10:24 AM in the morning, and the last departure from Wesley Chapel is at 5:24 PM which arrives into Key Largo at 9:20 AM. All services require a transfer at Wiregrass Park n Ride and take an average of 17h 35m. The schedules shown below are for the next available departures.
Arrives next day



20h • 3 changes
Arrives next day



18h 55m • 3 changes
Arrives next day



18h • 3 changes
Arrives next day



15h 55m • 3 changes
Want to know about travelling from Wesley Chapel to Key Largo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Wesley Chapel to Key Largo. However, there are services departing from Wesley Chapel station and arriving at Key Largo station via Miami Airport. The journey, including transfers, takes approximately 17h 35m.
Wesley Chapel to Key Largo bus services, operated by Pasco County Public Transportation, depart from University of South Florida - 3801 USF Holly Dr station.
Wesley Chapel to Key Largo bus services, operated by Pasco County Public Transportation, arrive at Key Largo Bus Stop station.
The distance between Wesley Chapel and Key Largo is 397.2 km. The road distance is 589 km.
You can take a bus from SR 54 & Saddlebrook Way to Key Largo Bus Stop via Wiregrass Park n Ride, University Area Transit Center, UATC to Mall/ Library, University of South Florida - 3801 USF Holly Dr, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, and Miami Airport Station in around 11h 10m.