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Tarpon Springs to Key Largo buses

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Trip Overview

The average bus between Tarpon Springs and Key Largo takes 17h 37m and the fastest bus takes 14h 24m. The bus service runs several times per day from Tarpon Springs to Key Largo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

17h 37m
Duration
390 mi
Distance
$81
Average price
Twice daily
Frequency

Tarpon Springs to Key Largo bus times

Buses run twice daily between Tarpon Springs and Key Largo. The earliest departure is at 9:55 AM in the morning, and the last departure from Tarpon Springs is at 6:56 PM which arrives into Key Largo at 9:20 AM. All services require a transfer at Sr 580 + Summerdale and take an average of 17h 37m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA19h 30m • 4 changes
  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA17h 25m • 4 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitGreyhound USAGreyhound USA20h 30m • 4 changes
  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA17h 25m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA19h 30m • 4 changes
  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA14h 25m • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA19h 30m • 4 changes
  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA14h 25m • 4 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA19h 30m • 4 changes
  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA14h 24m • 4 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA19h 30m • 4 changes
  •  → 

    Arrives next day

    Pinellas Suncoast Transit AuthorityPinellas Suncoast Transit AuthorityHillsborough Area Regional TransitFlixbus USAGreyhound USA15h 25m • 4 changes

Frequently asked questions

Want to know about travelling from Tarpon Springs to Key Largo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Tarpon Springs to Key Largo.ExpandLaunch map view
  • Distance: 390 mi
  • Duration: 17h 37m

What companies run services between Tarpon Springs, FL, USA and Key Largo, FL, USA?

You can take a bus from Huey Ave + Tarpon Ave to Key Largo Bus Stop via Sr 580 + Summerdale, Northwest Transfer Center, Tampa Bus Station, and Miami Airport Station in around 12h 45m.

Operators