The average bus between Tarpon Springs and Key Largo takes 18h 16m and the fastest bus takes 15h 9m. The bus service runs several times per day from Tarpon Springs to Key Largo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Tarpon Springs and Key Largo. The earliest departure is at 9:10 AM in the morning, and the last departure from Tarpon Springs is at 6:10 PM which arrives into Key Largo at 9:20 AM. All services require a transfer at Park St Terminal - Platform - H and take an average of 18h 16m. The schedules shown below are for the next available departures.
Arrives next day




20h 14m • 4 changes
Arrives next day




18h 9m • 4 changes
Arrives next day




21h 14m • 4 changes
Arrives next day




18h 9m • 4 changes
Arrives next day




20h 14m • 4 changes
Arrives next day




15h 9m • 4 changes
Want to know about travelling from Tarpon Springs to Key Largo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Tarpon Springs to Key Largo. However, there are services departing from Tarpon Springs station and arriving at Key Largo station via North West Transfer Center Tampa. The journey, including transfers, takes approximately 18h 16m.
Tarpon Springs to Key Largo bus services, operated by Pinellas Suncoast Transit Authority, depart from Park St Terminal - Platform - H station.
Tarpon Springs to Key Largo bus services, operated by Pinellas Suncoast Transit Authority, arrive at Key Largo Bus Stop station.
The distance between Tarpon Springs and Key Largo is 410.4 km. The road distance is 656 km.
You can take a bus from Pinellas Ave S + Court St W to Key Largo Bus Stop via Park St Terminal - Platform - H, Northwest Transfer Center, Marion Transit Center, Tampa Bus Station, and Miami Airport Station in around 14h 29m.