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How to get fromWaltham to St. Louisby plane, train (Amtrak), bus (Greyhound, Flixbus) or car

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There are 4 ways to get from Waltham to St. Louis by plane, train (Amtrak), bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane plane BOS - STL
    6h 2m
    $250–640
  2. Train (Amtrak)

    cheapest
    1. Take the train from Boston to Chicago Union Stationtrain train Lake Shore Limited
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    29h 13m
    $137–764
  3. Bus

    1. Take the bus from Boston to Newark Penn Stationbus bus Greyhound US0235 / ...
    2. Take the bus from Newark Penn Station to St Louis Bus Stationbus bus Greyhound US0421
    29h 43m
    $137–289
  4. Drive 1,142.3 mi

    1. Drive from Waltham to St. Louiscar car 1,142.3 mi
    20h 16m
    $209–302

Waltham to St. Louis by bus and train (Amtrak)

Calendar7Weekly Services
Duration29h 13mAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

What companies run services between Waltham, MA, USA and St. Louis, MO, USA?

American Airlines, Southwest Airlines, and Delta fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Washington St @ Bacon St to St. Louis via Stuart St @ Dartmouth St, Boston, and Chicago Union Station in around 29h 13m.

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