There are 4 ways to get from Waltham to St. Louis by plane, train (Amtrak), bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL)plane BOS - STL
6h 2m$250–640Train (Amtrak)
cheapest- Take the train from Boston to Chicago Union Stationtrain Lake Shore Limited
- Take the train from Chicago Union Station to St. Louistrain Lincoln Service / ...
29h 13m$137–764Bus
- Take the bus from Boston to Newark Penn Stationbus Greyhound US0235 / ...
- Take the bus from Newark Penn Station to St Louis Bus Stationbus Greyhound US0421
29h 43m$137–289Drive 1,142.3 mi
- Drive from Waltham to St. Louiscar 1,142.3 mi
20h 16m$209–302
Waltham to St. Louis by bus and train (Amtrak)
Questions & Answers
The cheapest way to get from Waltham to St. Louis is to bus which costs $130 - $290 and takes 29h 43m.
The fastest way to get from Waltham to St. Louis is to fly which takes 6h 2m and costs $250 - $650.
No, there is no direct bus from Waltham station to St. Louis station. However, there are services departing from Carter St opp Commuter Rail Station and arriving at St Louis Bus Station via Boston and Newark Penn Station. The journey, including transfers, takes approximately 29h 43m.
The distance between Waltham and St. Louis is 1082 miles. The road distance is 1149 miles.
The best way to get from Waltham to St. Louis without a car is to train which takes 29h 13m and costs $130 - $800.
It takes approximately 6h 2m to get from Waltham to St. Louis, including transfers.
Waltham to St. Louis bus services, operated by Greyhound USA, depart from Boston station.
The best way to get from Waltham to St. Louis is to fly which takes 6h 2m and costs $250 - $650. Alternatively, you can train, which costs $130 - $800 and takes 29h 13m, you could also bus, which costs $130 - $290 and takes 29h 43m.
Waltham to St. Louis bus services, operated by Greyhound USA, arrive at Newark Penn Station.
St. Louis is 1h behind Waltham. It is currently 5:04 PM in Waltham and 4:04 PM in St. Louis.
What companies run services between Waltham, MA, USA and St. Louis, MO, USA?
American Airlines, Southwest Airlines, and Delta fly from Boston Logan Airport (BOS) to Lambert–St. Louis International Airport (STL) every 4 hours. Alternatively, you can take a bus from Washington St @ Bacon St to St. Louis via Stuart St @ Dartmouth St, Boston, and Chicago Union Station in around 29h 13m.
- Website
- aa.com
Flights from Boston Logan Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 3h 25m
- When
- Every day
- Estimated price
- $170–850
- Website
- southwest.com
Flights from Boston Logan Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- $170–850
Flights from Boston Logan Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 42m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $170–900
- Website
- delta.com
Flights from Boston Logan Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $170–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Boston to Chicago Union Station
- Ave. Duration
- 22h 15m
- Frequency
- Once daily
- Estimated price
- $100–650
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Louis
- Ave. Duration
- 4h 46m
- Frequency
- 5 times a day
- Estimated price
- $35–110
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 4 times a day
- Estimated price
- $35–60
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to St Louis Bus Station
- Ave. Duration
- 22h 10m
- Frequency
- Once daily
- Estimated price
- $100–220
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Boston to Newark Penn Station
- Ave. Duration
- 4h 50m
- Frequency
- 3 times a day
- Estimated price
- $35–65
- Schedules at
- flixbus.com
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More Questions & Answers
Yes, the driving distance between Waltham to St. Louis is 1149 miles. It takes approximately 20h 16m to drive from Waltham to St. Louis.
There are 345+ hotels available in St. Louis.






