The average bus between Trieste and Mendrisio takes 12h 50m and the fastest bus takes 10h 12m. The bus service runs several times per day from Trieste to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Trieste and Mendrisio. The earliest departure is at 9:10 AM in the morning, and the last departure from Trieste is at 10:55 PM which arrives into Mendrisio at 9:34 AM. All services require a transfer at Milan and take an average of 12h 50m. The schedules shown below are for the next available departures.



10h 12m • 3 changesArrives next day



17h 49m • 3 changesArrives next day



10h 39m • 3 changesArrives next day



17h 37m • 3 changesArrives next day



10h 39m • 3 changesArrives next day



17h 37m • 3 changesArrives next day



10h 39m • 3 changes


10h 12m • 3 changesArrives next day



17h 37m • 3 changesArrives next day



10h 39m • 3 changesWant to know about travelling from Trieste to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Trieste to Mendrisio. However, there are services departing from Trieste station and arriving at Mendrisio station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 12h 50m.
Trieste to Mendrisio bus services, operated by FlixBus, depart from Trieste station.
Trieste to Mendrisio bus services, operated by FlixBus, arrive at Como station.
The distance between Trieste and Mendrisio is 372.3 km. The road distance is 485 km.
You can take a bus from Trieste to Mendrisio, Autosilo via Milan, Como, Como - San Rocchetto, and Chiasso, Stazione in around 8h 54m.