The average bus between Nice and Mendrisio takes 12h 51m and the fastest bus takes 9h 21m. The bus service runs several times per day from Nice to Mendrisio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Nice and Mendrisio. The earliest departure is at 12:11 AM at night, and the last departure from Nice is at 3:04 PM which arrives into Mendrisio at 7:34 AM. All services require a transfer at Aéroport / Promenade and take an average of 12h 51m. The schedules shown below are for the next available departures.




9h 21m • 4 changes




11h 56m • 4 changes
Arrives next day




20h • 4 changes




9h 21m • 4 changes




11h 56m • 4 changes
Arrives next day




16h 30m • 4 changes
Want to know about travelling from Nice to Mendrisio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Nice to Mendrisio. However, there are services departing from Nice station and arriving at Mendrisio station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 12h 51m.
Nice to Mendrisio bus services, operated by Lignes d'Azur, depart from Nice - Airport Bus Station Terminal 1.
Nice to Mendrisio bus services, operated by Lignes d'Azur, arrive at Como station.
The distance between Nice and Mendrisio is 276.7 km. The road distance is 392 km.
You can take a bus from Jardin d'Arménie to Mendrisio, Autosilo via Aéroport / Promenade, Nice - Airport Bus Station Terminal 1, Milan, Como, Como - San Rocchetto, and Chiasso, Stazione in around 9h 4m.