The average bus between Toronto and Depew takes 5h 51m and the fastest bus takes 4h 59m. The bus service runs several times per day from Toronto to Depew. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Toronto and Depew. The earliest departure is at 8:00 AM in the morning, and the last departure from Toronto is at 9:30 PM which arrives into Depew at 5:38 AM. All services require a transfer, and take on average 5h 51m. The schedules shown below are for the next available departures.

5h 1m • 1 change

6h 2m • 1 change

5h 5m • 1 change

4h 59m • 1 change

5h 1m • 1 change

6h 2m • 1 change

5h 5m • 1 change

4h 59m • 1 change

5h 1m • 1 change

6h 2m • 1 change

5h 5m • 1 change

4h 59m • 1 change
Want to know about travelling from Toronto to Depew? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Toronto to Depew. However, there are services departing from Toronto station and arriving at Depew station via Buffalo. The journey, including transfers, takes approximately 5h 51m.
Toronto to Depew bus services, operated by Greyhound USA, depart from Toronto station.
Toronto to Depew bus services, operated by Greyhound USA, arrive at Broadway & Elwood Avenue station.
The distance between Toronto and Depew is 100.4 km. The road distance is 192 km.
You can take a bus from Toronto to Broadway & Elwood Avenue via Ellicott Street & MTC Static in around 4h 54m.