The average bus between Times Square and Hyannis takes 6h 48m and the fastest bus takes 6h 15m. The bus service runs several times per day from Times Square to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 2 hours between Times Square and Hyannis. The earliest departure is at 1:30 AM at night, and the last departure from Times Square is at 7:00 PM which arrives into Hyannis at 1:35 AM. All services require a transfer at Boston and take an average of 6h 48m. The schedules shown below are for the next available departures.

7h 15m • 1 change

6h 50m • 1 change
Arrives next day

6h 35m • 1 change

6h 45m • 1 change

7h 40m • 1 change

6h 15m • 1 change

7h • 1 change

6h 45m • 1 change

7h 40m • 1 change

6h 15m • 1 change

7h • 1 change

6h 45m • 1 change

7h 40m • 1 change

6h 15m • 1 change

7h • 1 change

6h 45m • 1 change

7h 40m • 1 change

6h 15m • 1 change

7h • 1 change

6h 45m • 1 change

7h 40m • 1 change

6h 15m • 1 change

7h • 1 change
Want to know about travelling from Times Square to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Times Square to Hyannis. However, there are services departing from Times Square station and arriving at Hyannis station via Boston. The journey, including transfers, takes approximately 6h 48m.
Times Square to Hyannis bus services, operated by Flixbus USA, depart from New York Midtown station.
Times Square to Hyannis bus services, operated by Flixbus USA, arrive at Hyannis Transportation Center station.
The distance between Times Square and Hyannis is 325.5 km. The road distance is 460 km.
You can take a bus from New York Midtown to Hyannis Transportation Center via Boston and Boston South Buses in around 6h 52m.