The average bus between Indianapolis and Hyannis takes 29h 22m and the fastest bus takes 25h 25m. The bus service runs several times per day from Indianapolis to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Indianapolis and Hyannis. The earliest departure is at 12:15 AM at night, and the last departure from Indianapolis is at 12:05 PM which arrives into Hyannis at 1:30 PM. All services require a transfer at New York Midtown and take an average of 29h 22m. The schedules shown below are for the next available departures.
Arrives next day


33h 20m • 2 changes
Arrives next day


25h 25m • 2 changes
Arrives next day


33h 20m • 2 changes
Arrives next day


25h 25m • 2 changes
Arrives next day


33h 20m • 2 changes
Arrives next day


25h 25m • 2 changes
Want to know about travelling from Indianapolis to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Indianapolis to Hyannis. However, there are services departing from Indianapolis station and arriving at Hyannis station via New York Midtown. The journey, including transfers, takes approximately 29h 22m.
Indianapolis to Hyannis bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to Hyannis bus services, operated by Flixbus USA, arrive at Hyannis Transportation Center station.
Book your Indianapolis to Hyannis bus tickets online with Flixbus USA and Peter Pan Bus Lines.
The distance between Indianapolis and Hyannis is 1,352.4 km. The road distance is 1,753 km.
You can take a bus from Indianapolis to Hyannis Transportation Center via New York Midtown, Boston, and Boston South Station in around 23h 53m.