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Tampa to Key West buses

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Trip Overview

The average bus between Tampa and Key West takes 16h 50m and the fastest bus takes 14h 27m. There is at least one bus per day from Tampa to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

16h 50m
Duration
447 mi
Distance
$93
Average price
Once daily
Frequency

Tampa to Key West bus times

Buses run once daily between Tampa and Key West. The earliest departure is at 1:45 PM in the afternoon, and the last departure from Tampa is at 10:35 PM which arrives into Key West at 3:42 PM. All services require a transfer at Miami Airport Station and take an average of 16h 50m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit21h 47m • 2 changes
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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit17h 7m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USAKey West Transit23h 17m • 2 changes
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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit17h 7m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit14h 27m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit14h 27m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit14h 27m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit14h 27m • 2 changes

Frequently asked questions

Want to know about travelling from Tampa to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Tampa to Key West.ExpandLaunch map view
  • Distance: 446.7 mi
  • Duration: 16h 50m

What companies run services between Tampa, FL, USA and Key West, FL, USA?

You can take a bus from Tampa Bus Station to N Roosevelt & 3rd Street via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 12h 56m.

Operators