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Gainesville to Key West buses

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Trip Overview

The average bus between Gainesville and Key West takes 26h 4m and the fastest bus takes 24h 57m. The bus runs, on average, 6 times per week from Gainesville to Key West. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

26h 4m
Duration
517 mi
Distance
$99
Average price
6 times a week
Frequency

Gainesville to Key West bus times

Buses run 6 times a week between Gainesville and Key West. The earliest departure is at 5:20 AM in the morning, and the last departure from Gainesville is at 12:05 PM which arrives into Key West at 1:02 PM. All services require a transfer at Miami Airport Station and take an average of 26h 4m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit24h 57m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit24h 57m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit24h 57m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit31h 42m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit24h 57m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Flixbus USAGreyhound USAKey West Transit24h 57m • 2 changes

Frequently asked questions

Want to know about travelling from Gainesville to Key West? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Gainesville to Key West.ExpandLaunch map view
  • Distance: 516.5 mi
  • Duration: 26h 4m

What companies run services between Gainesville, FL, USA and Key West, FL, USA?

You can take a bus from Gainesville to N Roosevelt & 3rd Street via Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 15h 11m.

Operators