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How to get fromSt. Louis to Independenceby train (Amtrak), bus (Greyhound), car, plane or bus

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There are 4 ways to get from St. Louis to Independence by train (Amtrak), bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from St. Louis to Independence StationtrainMissouri River Runner / ...
    5h 10m
    $30–65
  2. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Kansas City Bus StationbusGreyhound US1200 / ...
    6h 13m
    $36–77
  3. Drive 239.6 mi

    1. Drive from St. Louis to Independencecar239.6 mi
    4h 6m
    $44–64
  4. Fly, line 24 bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Kansas City (MCI)planeSTL - MCI
    2. Take the bus from East Village - Bay A to On White Oak At Osage Ebbus
    5h 50m
    $182–702

St. Louis to Independence by train (Amtrak)

Calendar14Weekly Trains
Duration5h 10mAverage Duration
Ticket$30Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Independence, MO, USA?

Amtrak operates a train from St. Louis to Independence Station twice daily. Tickets cost $30–65 and the journey takes 5h 10m. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Kansas City Bus Station 4 times a day. Tickets cost $35–80 and the journey takes 4h 30m.

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