There are 4 ways to get from St. Louis to Independence by train (Amtrak), bus (Greyhound), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from St. Louis to Independence StationMissouri River Runner / ...
5h 10m$30–65Bus (Greyhound)
- Take the bus from St Louis Bus Station to Kansas City Bus StationGreyhound US1200 / ...
6h 13m$36–77Drive 239.6 mi
- Drive from St. Louis to Independence239.6 mi
4h 6m$44–64Fly, line 24 bus
- Fly from Lambert–St. Louis International Airport (STL) to Kansas City (MCI)STL - MCI
- Take the bus from East Village - Bay A to On White Oak At Osage Eb
5h 50m$182–702
St. Louis to Independence by train (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Independence is to train which costs $30 - $65 and takes 5h 10m.
The fastest way to get from St. Louis to Independence is to drive which takes 4h 6m and costs $40 - $65.
No, there is no direct bus from St. Louis station to Independence. However, there are services departing from St Louis Bus Station and arriving at On White Oak At Osage Eb via East Village - Bay A. The journey, including transfers, takes approximately 6h 13m.
Yes, there is a direct train departing from St. Louis and arriving at Independence Station station. Services depart twice daily, and operate every day. The journey takes approximately 5h 10m.
The distance between St. Louis and Independence is 270 miles. The road distance is 241 miles.
The best way to get from St. Louis to Independence without a car is to train which takes 5h 10m and costs $30 - $65.
The train from St. Louis to Independence Station takes 5h 10m including transfers and departs twice daily.
St. Louis to Independence bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Independence train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Independence is to train which takes 5h 10m and costs $30 - $65. Alternatively, you can bus, which costs $35 - $80 and takes 6h 13m.
What companies run services between St. Louis, MO, USA and Independence, MO, USA?
Amtrak operates a train from St. Louis to Independence Station twice daily. Tickets cost $30–65 and the journey takes 5h 10m. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Kansas City Bus Station 4 times a day. Tickets cost $35–80 and the journey takes 4h 30m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Kansas City
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $95–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Independence Station
- Ave. Duration
- 5h 10m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a day
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
- Phone
- +1 816-221-0660
- Website
- ridekc.org
Bus from East Village - Bay A to On White Oak At Osage Eb
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Schedules at
- ridekc.org
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More Questions & Answers
St. Louis to Independence bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
St. Louis to Independence train services, operated by Amtrak, arrive at Independence Station.
Yes, the driving distance between St. Louis to Independence is 241 miles. It takes approximately 4h 6m to drive from St. Louis to Independence.
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There are 236+ hotels available in Independence.






