The average bus between Pittsburgh and Independence takes 25h 32m and the fastest bus takes 21h 3m. There is at least one bus per day from Pittsburgh to Independence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Pittsburgh and Independence. The earliest departure is at 1:25 AM at night, and the last departure from Pittsburgh is at 10:50 AM which arrives into Independence at 6:53 AM. All services require a transfer at St Louis Bus Station and take an average of 25h 32m. The schedules shown below are for the next available departures.
Arrives next day


28h 16m • 2 changes
Arrives next day


20h 54m • 2 changes
Arrives next day


28h 16m • 2 changes
Arrives next day


20h 54m • 2 changes
Want to know about travelling from Pittsburgh to Independence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pittsburgh to Independence. However, there are services departing from Pittsburgh station and arriving at Independence station via St Louis Bus Station station. The journey, including transfers, takes approximately 25h 32m.
Pittsburgh to Independence bus services, operated by Greyhound USA, depart from Pittsburgh Intermodal Station.
Pittsburgh to Independence bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
The distance between Pittsburgh and Independence is 1,240.2 km. The road distance is 1,392 km.
You can take a bus from Pittsburgh Intermodal Station to On White Oak At Osage Eb via St Louis Bus Station, Kansas City Bus Station, and East Village - Bay A in around 19h 39m.