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St. Louis to Hyannis buses

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Trip Overview

The average bus between St. Louis and Hyannis takes 35h 38m and the fastest bus takes 32h. The bus service runs several times per day from St. Louis to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

35h 38m
Duration
1,336 mi
Distance
$250
Average price
Twice daily
Frequency

Bus

best
  1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
  2. Take the bus from New York Midtown to Bostonbus bus
  3. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
32h 50m

St. Louis to Hyannis bus times

Buses run twice daily between St. Louis and Hyannis. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Hyannis at 9:35 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 35h 38m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from St. Louis to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Hyannis.ExpandLaunch map view
  • Distance: 1,335.9 mi
  • Duration: 35h 38m

What companies run services between St. Louis, MO, USA and Hyannis, MA, USA?

You can take a bus from St Louis Bus Station to Hyannis Transportation Center via Port Authority Bus Terminal, New York Midtown, Boston, and Boston South Station in around 32h 50m.

Operators