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St. Louis to Hyannis buses

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Trip Overview

The average bus between St. Louis and Hyannis takes 36h 14m and the fastest bus takes 32h. The bus service runs several times per day from St. Louis to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

36h 14m
Duration
1,334 mi
Distance
$281
Average price
Twice daily
Frequency

Bus

best
  1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
  2. Take the bus from New York to Bostonbus bus
  3. Take the bus from South Station Transp. Ctr to Hyannis Transportation Centerbus bus
32h 30m
$238–468

St. Louis to Hyannis bus times

Buses run twice daily between St. Louis and Hyannis. The earliest departure is at 2:00 AM at night, and the last departure from St. Louis is at 2:05 PM which arrives into Hyannis at 9:35 AM. All services require a transfer at Port Authority Bus Terminal and take an average of 36h 14m. The schedules shown below are for the next available departures.

Frequently asked questions

Want to know about travelling from St. Louis to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from St. Louis to Hyannis.ExpandLaunch map view
  • Distance: 1,334.2 mi
  • Duration: 36h 14m

What companies run services between St. Louis, MO, USA and Hyannis, MA, USA?

You can take a bus from St Louis Bus Station to Hyannis Transportation Center via Port Authority Bus Terminal, New York, and South Station Transp. Ctr in around 32h 30m.

Operators