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How to get fromSt. Louis to Hyannisby plane, train, bus, bus (Greyhound), car or bus (Greyhound, Flixbus)

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There are 6 ways to get from St. Louis to Hyannis by plane, train, bus, bus (Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barnstable Municipal Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Barnstable Municipal Airport (HYA)plane plane STL - HYA
    6h 15m
    $152–752

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    2. Take the bus from Port Authority Bus Terminal to Peter Pan Bus Terminalbus bus
    3. Take the bus from Providence Bus Terminal to Hyannis Transportation Centerbus bus
    32h 35m
    $114–323

  3. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Bostontrain train
    3. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    30h 29m
    $153–668

  4. Drive 1,185.3 mi

    1. Drive from St. Louis to Hyanniscar car 1,185.3 mi
    21h 15m
    $217–313

  5. Fly to Boston Logan Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS)plane plane STL - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 52m
    $270–642

  6. Bus via Boston

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    2. Take the bus from New York Midtown to Bostonbus bus
    3. Take the bus from Boston South Station to Hyannis Transportation Centerbus bus
    32h 49m
    $118–328

St. Louis to Hyannis by train and bus

Calendar7Weekly Services
Duration30h 29mAverage Duration
Ticket$153Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Hyannis, MA, USA?

American Airlines, Southwest Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Barnstable Municipal Airport (HYA) 4 times a day. Alternatively, you can take a bus from St Louis Bus Station to Hyannis Transportation Center via Port Authority Bus Terminal and Providence Bus Terminal in around 32h 35m.

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