The average bus between Siena and Vasto takes 7h 49m and the fastest bus takes 6h 20m. The bus service runs several times per day from Siena to Vasto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Siena and Vasto. The earliest departure is at 7:00 AM in the morning, and the last departure from Siena is at 10:25 PM which arrives into Vasto at 11:50 AM. All services require a transfer, and take on average 7h 49m. The schedules shown below are for the next available departures.

6h 50m • 1 change

6h 20m • 1 change

7h 5m • 1 change

6h 40m • 1 change

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7h 5m • 1 change

8h 25m • 1 change

6h 50m • 1 change

6h 20m • 1 change

7h 5m • 1 change

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6h 50m • 1 change

6h 20m • 1 change

7h 5m • 1 change

6h 50m • 1 change

6h 50m • 1 change

6h 20m • 1 change

7h 5m • 1 change

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6h 50m • 1 change

6h 20m • 1 change

7h 5m • 1 change

6h 50m • 1 change
Want to know about travelling from Siena to Vasto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Vasto. However, there are services departing from Siena station and arriving at Vasto station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 7h 49m.
Siena to Vasto bus services, operated by FlixBus, depart from Siena station.
Siena to Vasto bus services, operated by FlixBus, arrive at Vasto station.
Book your Siena to Vasto bus tickets online with FlixBus, Dicarlo Bus and AutoLinee Moretti.
The distance between Siena and Vasto is 306.7 km. The road distance is 502 km.
You can take a bus from Siena to Vasto via Roma, Autostazione Tiburtina in around 7h 20m.