The average bus between Siena and Mainz takes 23h 45m and the fastest bus takes 20h 35m. There is at least one bus per day from Siena to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Siena and Mainz. The earliest departure is at 11:40 AM in the morning, and the last departure from Siena is at 6:10 PM which arrives into Mainz at 5:30 PM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 23h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Siena to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Mainz. However, there are services departing from Siena station and arriving at Mainz station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 23h 45m.
Siena to Mainz bus services, operated by FlixBus, depart from Siena station.
Siena to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Book your Siena to Mainz bus tickets online with FlixBus.
The distance between Siena and Mainz is 776.8 km. The road distance is 1,157 km.
You can take a bus from Siena to Mainz central train station via Florence Villa Constanza Bus Station and Frankfurt central train station in around 21h.
