The average bus between Siena and Mainz takes 21h 10m and the fastest bus takes 19h 50m. The bus runs, on average, 6 times per week from Siena to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Siena and Mainz. The earliest departure is at 10:25 AM in the morning, and the last departure from Siena is at 10:25 AM which arrives into Mainz at 8:15 AM. All services require a transfer at Bologna Centrale and take an average of 21h 10m. The schedules shown below are for the next available departures.
Want to know about travelling from Siena to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Siena to Mainz. However, there are services departing from Siena station and arriving at Mainz station via Bologna. The journey, including transfers, takes approximately 21h 10m.
Siena to Mainz bus services, operated by FlixBus, depart from Siena station.
Siena to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Book your Siena to Mainz bus tickets online with FlixBus.
The distance between Siena and Mainz is 776.8 km. The road distance is 1,161 km.
You can take a bus from Siena to Mainz central train station via Bologna Centrale and Frankfurt central train station in around 18h 10m.
