The bus between Rome and Mainz takes 26h 55m. The bus runs, on average, 6 times per week from Rome to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Rome and Mainz. The earliest departure is at 4:35 PM in the afternoon, and the last departure from Rome is at 4:35 PM which arrives into Mainz at 5:30 PM. All services require a transfer, and take on average 26h 55m. The schedules shown below are for the next available departures.
Want to know about travelling from Rome to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Rome to Mainz. However, there are services departing from Rome station and arriving at Mainz station via Frankfurt central train station station. The journey, including transfers, takes approximately 26h 55m.
Rome to Mainz bus services, operated by FlixBus, depart from Roma, Autostazione Tiburtina station.
Rome to Mainz bus services, operated by FlixBus, arrive at Frankfurt central train station.
Book your Rome to Mainz bus tickets online with FlixBus.
The distance between Rome and Mainz is 955.8 km. The road distance is 1,366 km.
FlixBus operates a bus from Roma, Autostazione Tiburtina to Frankfurt central train station once daily. Tickets cost €90–160 and the journey takes 20h 55m.