There are 8 ways to get from Siena to Mainz by train, plane, train (Trenitalia), bus, car, or car train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Florence Peretola Airport, fly
best- Take the train from Siena to Firenze S.M.N.
- Fly from Florence Peretola Airport (FLR) to Frankfurt (FRA)FLR - FRA
6h 7m€116–285Bus
cheapest- Take the bus from Siena to Florence Villa Constanza Bus Station1509 / ...
- Take the bus from Florence Villa Constanza Bus Station to Frankfurt central train stationN77 / ...
21h€57–156Train
- Take the train from Siena to Firenze S.M.N.Re
- Take the train from Firenze S.M.N. to Milano CentraleFr
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
13h 28m€165–295Bus, train
- Take the bus from Siena Central Train Station to Milan
- Take the bus from Milan to Mannheim Central Bus Station
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
19h 26m€86–153Drive 1,023.5 km
- Drive from Siena to Mainz1,023.5 km
9h 45m€158–228Train, train to Bologna Guglielmo Marconi Airport, fly
- Take the train from Siena to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Bologna Centrale
- Fly from Bologna Guglielmo Marconi Airport (BLQ) to Frankfurt (FRA)BLQ - FRA
6h 40m€127–342Train via Siena
- Take the train from Siena to Firenze S.M.N.Re
- Take the train from Florence Santa Maria Novella to Milano Centrale
- Take the train from Milano Centrale to Mannheim HbfEc
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
13h 42m€166–280Drive, car train
- Drive from Siena to München Ost
- Take the car train from München Ost to Würzburg Hbf
- Drive from Würzburg Hbf to Mainz
10h€214–291
Siena to Mainz by train
Questions & Answers
The cheapest way to get from Siena to Mainz is to bus which costs €55 - €160 and takes 21h.
The fastest way to get from Siena to Mainz is to train and fly which takes 6h 7m and costs €110 - €290.
No, there is no direct bus from Siena to Mainz station. However, there are services departing from Siena and arriving at Mainz central train station via Florence Villa Constanza Bus Station and Frankfurt central train station. The journey, including transfers, takes approximately 21h.
No, there is no direct train from Siena to Mainz. However, there are services departing from Siena and arriving at Mainz, Römisches Theater via Firenze S.M.N., Milano Centrale and Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 13h 28m.
The distance between Siena and Mainz is 847 km. The road distance is 1023.5 km.
The best way to get from Siena to Mainz without a car is to train which takes 13h 28m and costs €160 - €300.
It takes approximately 6h 7m to get from Siena to Mainz, including transfers.
Siena to Mainz bus services, operated by FlixBus, depart from Siena station.
Siena to Mainz train services, operated by Trenitalia S.p.A., depart from Siena station.
The best way to get from Siena to Mainz is to train which takes 13h 28m and costs €160 - €300. Alternatively, you can bus, which costs €55 - €160 and takes 21h.
What companies run services between Siena, Italy and Mainz, Germany?
You can take a train from Siena to Mainz, Römisches Theater via Firenze S.M.N., Milano Centrale, Mannheim Hbf, and Mannheim, Hauptbahnhof in around 13h 28m. Alternatively, you can take a bus from Siena to Mainz central train station via Florence Villa Constanza Bus Station and Frankfurt central train station in around 21h.
- Website
- lufthansa.com
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €100–250
Flights from Florence Peretola Airport to Frankfurt via Munich
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €100–250
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–320
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Munich
- Ave. Duration
- 3h 30m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €100–330
- Website
- airdolomiti.it
Flights from Florence Peretola Airport to Frankfurt
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €100–250
Flights from Bologna Guglielmo Marconi Airport to Frankfurt
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- €100–320
- Website
- swiss.com
Flights from Florence Peretola Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €85–340
Flights from Bologna Guglielmo Marconi Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €70–280
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Siena to Firenze S.M.N.
- Ave. Duration
- 1h 34m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 44m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €30–85
- Schedules at
- trenitalia.com
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €15–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Firenze S.M.N. to Milano Centrale
- Ave. Duration
- 3h 54m
- Frequency
- Once daily
- Estimated price
- €25–65
- Website
- https://www.trenitalia.com/en.html
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 17m
- Frequency
- Once daily
- Estimated price
- €10–15
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Milano Centrale to Mannheim Hbf
- Ave. Duration
- 6h 48m
- Frequency
- Once daily
- Estimated price
- €120–180
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €120–180
- 2nd Class
- €120–160
Train from Firenze S.M.N. to Bologna Centrale
- Ave. Duration
- 1h 12m
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Hourly
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Florence Santa Maria Novella to Milano Centrale
- Ave. Duration
- 1h 55m
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://www.italotreno.it/en
- Phone
- +49 (0) 221 800 20 820
- info@urlaubs-express.de
- Website
- urlaubs-express.de
Car train from München Ost to Würzburg Hbf
- Ave. Duration
- 1h 37m
- Frequency
- Once daily
- Estimated price
- €90–110
- Website
- https://urlaubs-express.de/?lang=en
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Siena Central Train Station to Milan
- Ave. Duration
- 5h 14m
- Frequency
- 6 times a week
- Estimated price
- €18–65
- Website
- https://www.itabus.it/en/home
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 55 min
- Frequency
- 4 times a day
- Estimated price
- €12–13
- Website
- https://www.itabus.it/en/home
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Milan to Mannheim Central Bus Station
- Ave. Duration
- 11h 35m
- Frequency
- Twice a week
- Estimated price
- €55–70
- Website
- https://marinobus.it/en/
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 1h
- Frequency
- Once daily
- Estimated price
- €7–10
- Website
- https://marinobus.it/en/
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Siena to Florence Villa Constanza Bus Station
- Ave. Duration
- 50 min
- Frequency
- Every 2 hours
- Estimated price
- €11–19
- Website
- https://www.flixbus.co.uk
Bus from Florence Villa Constanza Bus Station to Frankfurt central train station
- Ave. Duration
- 17h 30m
- Frequency
- Twice daily
- Estimated price
- €45–130
- Website
- https://www.flixbus.co.uk
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More Questions & Answers
Siena to Mainz bus services, operated by FlixBus, arrive at Florence Villa Constanza Bus Station.
Siena to Mainz train services, operated by Trenitalia S.p.A., arrive at Firenze S.M.N. station.
Yes, the driving distance between Siena to Mainz is 1024 km. It takes approximately 9h 45m to drive from Siena to Mainz.
Book your Siena to Mainz train tickets online with Omio.
Book your Siena to Mainz bus tickets online with FlixBus.
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