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Sicily to Siena buses

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Trip Overview

The average bus between Sicily and Siena takes 20h 59m and the fastest bus takes 16h 50m. The bus runs, on average, 2 times per week from Sicily to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

20h 59m
Duration
1,212 km
Distance
€131
Average price
Twice a week
Frequency

Sicily to Siena bus times

Buses run twice a week between Sicily and Siena. The earliest departure is at 6:35 AM in the morning, and the last departure from Sicily is at 2:55 PM which arrives into Siena at 7:45 AM. All services require a transfer at Stazione Centrale Pensilina Esterna and take an average of 20h 59m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

  •  → 

    Arrives next day

    AMAT Palermo S.p.A.FlixBus16h 50m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    Arrives next day

    AMAT Palermo S.p.A.FlixBus25h 9m • 1 change

Frequently asked questions

Want to know about travelling from Sicily to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Sicily to Siena.ExpandLaunch map view
  • Distance: 1,212.2 km
  • Duration: 20h 59m

What companies run services between Sicily, Italy and Siena, Italy?

FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €100–160 and the journey takes 16h 20m.

Operators