There are 11 ways to get from Sicily to Siena by plane, train, ferry, car, train (Trenitalia), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Catania–Fontanarossa Airport to Florence Peretola Airport, train
best- Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)CTA - FLR
- Take the train from Firenze S.M.N. to Siena
5h 31m€46–185Bus via Naples
cheapest- Take the bus from Palermo Terminal Bus to Napoli, Autostazione MetroparkItabus
- Take the bus from Napoli, Autostazione Metropark to Siena Central Train StationItabus
19h 8m€30–88Ferry, drive
- Take the ferry from Port of Palermo to Port of Naples
- Drive from Port of Naples to Siena
12h 42m€106–156Train
- Take the train from Palermo Centrale to Roma TerminiIc
- Take the train from Roma Termini to Florence Santa Maria Novella
- Take the train from Firenze S.M.N. to SienaRe
17h 9m€67–184Bus
- Take the bus from Palermo to SienaN597
17h 43m€51–121Fly Palermo Airport to Florence Peretola Airport, train
- Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)PMO - FLR
- Take the train from Firenze S.M.N. to Siena
5h 59m€68–207Fly Palermo Airport to Pisa International Airport, train
- Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)PMO - PSA
- Take the train from Pisa Centrale to Empoli
- Take the train from Empoli to Siena
5h 43m€83–215Fly Catania–Fontanarossa Airport to Pisa International Airport, train
- Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)CTA - PSA
- Take the train from Pisa Centrale to Empoli
- Take the train from Empoli to Siena
5h 20m€66–203Fly Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport, train
- Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)CTA - BLQ
- Take the train from Bologna Centrale to Firenze S.M.N.
- Take the train from Firenze S.M.N. to Siena
6h 15m€51–262Fly Palermo Airport to Perugia Sant'Egidio Airport, bus
- Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)PMO - PEG
- Take the bus from Perugia to Siena
5h 38m€99–365Train via Chiusi
- Take the train from Palermo Centrale to Roma TerminiIc
- Take the train from Roma Termini to Chiusi-Chianciano T.Re
- Take the train from Chiusi-Chianciano T. to SienaRe
18h 1m€53–145
Sicily to Siena by train
Questions & Answers
The cheapest way to get from Sicily to Siena is to bus via Naples which costs €30 - €90 and takes 19h 8m.
The fastest way to get from Sicily to Siena is to fly and train which takes 5h 20m and costs €65 - €210.
No, there is no direct bus from Sicily to Siena. However, there are services departing from Piazza Boiardo and arriving at Siena via Palermo. The journey, including transfers, takes approximately 17h 43m.
No, there is no direct train from Sicily to Siena. However, there are services departing from Palermo Notarbartolo and arriving at Siena via Palermo Centrale, Roma Termini and Firenze S.M.N.. The journey, including transfers, takes approximately 17h 9m.
The distance between Sicily and Siena is 878 km.
The best way to get from Sicily to Siena without a car is to train which takes 17h 9m and costs €65 - €190.
It takes approximately 5h 31m to get from Sicily to Siena, including transfers.
Sicily to Siena bus services, operated by FlixBus, depart from Palermo station.
Sicily to Siena train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
The best way to get from Sicily to Siena is to train which takes 17h 9m and costs €65 - €190. Alternatively, you can bus, which costs €50 - €130 and takes 17h 43m.
What companies run services between Sicily, Italy and Siena, Italy?
You can take a train from Palermo Notarbartolo to Siena via Palermo Centrale, Roma Termini, and Firenze S.M.N. in around 17h 9m. Alternatively, FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €50–120 and the journey takes 16h 20m.
- Website
- ryanair.com
Flights from Palermo Airport to Pisa International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- €60–190
Flights from Palermo Airport to Pisa International Airport via Bari
- Ave. Duration
- 3h 30m
- When
- Tuesday
- Estimated price
- €60–190
Flights from Catania–Fontanarossa Airport to Pisa International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- €50–170
Flights from Catania–Fontanarossa Airport to Pisa International Airport via Malta
- Ave. Duration
- 3h 40m
- When
- Monday and Thursday
- Estimated price
- €50–170
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €50–140
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Cagliari
- Ave. Duration
- 3h 30m
- When
- Tuesday
- Estimated price
- €50–140
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Malta
- Ave. Duration
- 3h 35m
- When
- Tuesday
- Estimated price
- €50–140
Flights from Palermo Airport to Perugia Sant'Egidio Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €65–250
- Website
- ita-airways.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- €70–150
Flights from Palermo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 16m
- When
- Every day
- Estimated price
- €70–160
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport via Rome
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- €50–160
- Website
- volotea.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 40m
- When
- Every day
- Estimated price
- €26–150
Flights from Palermo Airport to Florence Peretola Airport
- Ave. Duration
- 1h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €30–170
- Website
- flyulendo.com
Flights from Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- €22–150
- Website
- vueling.com
Flights from Catania–Fontanarossa Airport to Florence Peretola Airport
- Ave. Duration
- 1h 35m
- When
- Wednesday and Saturday
- Estimated price
- €30–190
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €7–10
- Website
- https://www.trenitalia.com/en.html
Train from Pisa Centrale to Empoli
- Ave. Duration
- 45 min
- Frequency
- Every 30 minutes
- Estimated price
- €4–7
- Website
- https://www.trenitalia.com/en.html
Train from Empoli to Siena
- Ave. Duration
- 1h
- Frequency
- Hourly
- Estimated price
- €5–8
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Chiusi-Chianciano T. to Siena
- Ave. Duration
- 1h 31m
- Frequency
- Every 2 hours
- Estimated price
- €6–10
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Palermo Centrale to Roma Termini
- Ave. Duration
- 11h 29m
- Frequency
- Once daily
- Estimated price
- €35–110
- Website
- https://www.trenitalia.com/en.html
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 1h 16m
- Frequency
- Once daily
- Estimated price
- €9–15
- Website
- https://www.trenitalia.com/en.html
Train from Roma Termini to Chiusi-Chianciano T.
- Ave. Duration
- 1h 48m
- Frequency
- 3 times a day
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Roma Termini to Florence Santa Maria Novella
- Ave. Duration
- 1h 32m
- Frequency
- Hourly
- Estimated price
- €22–60
- Website
- https://www.italotreno.it/en
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 46 min
- Frequency
- Once a week
- Estimated price
- €15–35
- Website
- https://www.italotreno.it/en
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 37 min
- Frequency
- Every 30 minutes
- Estimated price
- €17–35
- Schedules at
- trenitalia.com
- Phone
- +39 06 68475475
- ufficiogruppi@trenitalia.it
- Website
- trenitalia.com
Train from Bologna Centrale to Firenze S.M.N.
- Ave. Duration
- 59 min
- Frequency
- Once daily
- Estimated price
- €27–70
- Website
- https://www.trenitalia.com/en.html
- 1st Class
- €45–70
- 2nd Class
- €27–40
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Palermo to Siena
- Ave. Duration
- 16h 20m
- Frequency
- Once daily
- Estimated price
- €50–120
- Website
- https://www.flixbus.co.uk
Bus from Perugia to Siena
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- €7–18
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Palermo Terminal Bus to Napoli, Autostazione Metropark
- Ave. Duration
- 10h 40m
- Frequency
- 3 times a week
- Estimated price
- €19–27
- Website
- https://www.itabus.it/en/home
Bus from Napoli, Autostazione Metropark to Siena Central Train Station
- Ave. Duration
- 6h 5m
- Frequency
- 4 times a day
- Estimated price
- €10–60
- Website
- https://www.itabus.it/en/home
- Phone
- +39.081.496.444
- info@grimaldi.napoli.it
- Website
- grimaldi-lines.com
Ferry from Port of Palermo to Port of Naples
- Ave. Duration
- 8h 30m
- Frequency
- 4 times a week
- Estimated price
- €40–55
- Website
- https://www.grimaldi-lines.com/en/
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More Questions & Answers
Sicily to Siena bus services, operated by FlixBus, arrive at Siena station.
Sicily to Siena train services, operated by Trenitalia Intercity, arrive at Roma Termini station.
Book your Sicily to Siena train tickets online with Omio.
There are 2228+ hotels available in Siena.































