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How to get fromSicily to Sienaby plane, train, ferry, car, train (Trenitalia) or bus

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There are 11 ways to get from Sicily to Siena by plane, train, ferry, car, train (Trenitalia), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Catania–Fontanarossa Airport to Florence Peretola Airport, train

    best
    1. Fly from Catania–Fontanarossa Airport (CTA) to Florence Peretola Airport (FLR)planeCTA - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain
    5h 31m
    €46–185
  2. Bus via Naples

    cheapest
    1. Take the bus from Palermo Terminal Bus to Napoli, Autostazione MetroparkbusItabus
    2. Take the bus from Napoli, Autostazione Metropark to Siena Central Train StationbusItabus
    19h 8m
    €30–83
  3. Ferry, drive

    1. Take the ferry from Port of Palermo to Port of Naplesferry
    2. Drive from Port of Naples to Sienacar
    12h 42m
    €106–156
  4. Train

    1. Take the train from Palermo Centrale to Roma TerminitrainIc
    2. Take the train from Roma Termini to Florence Santa Maria Novellatrain
    3. Take the train from Firenze S.M.N. to SienatrainRe
    17h 9m
    €67–184
  5. Bus

    1. Take the bus from Palermo to SienabusN597
    17h 43m
    €51–121
  6. Fly Palermo Airport to Florence Peretola Airport, train

    1. Fly from Palermo Airport (PMO) to Florence Peretola Airport (FLR)planePMO - FLR
    2. Take the train from Firenze S.M.N. to Sienatrain
    5h 59m
    €68–207
  7. Fly Palermo Airport to Pisa International Airport, train

    1. Fly from Palermo Airport (PMO) to Pisa International Airport (PSA)planePMO - PSA
    2. Take the train from Pisa Centrale to Empolitrain
    3. Take the train from Empoli to Sienatrain
    5h 43m
    €83–215
  8. Fly Catania–Fontanarossa Airport to Pisa International Airport, train

    1. Fly from Catania–Fontanarossa Airport (CTA) to Pisa International Airport (PSA)planeCTA - PSA
    2. Take the train from Pisa Centrale to Empolitrain
    3. Take the train from Empoli to Sienatrain
    5h 20m
    €66–203
  9. Fly Catania–Fontanarossa Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Catania–Fontanarossa Airport (CTA) to Bologna Guglielmo Marconi Airport (BLQ)planeCTA - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train
    3. Take the train from Firenze S.M.N. to Sienatrain
    6h 15m
    €51–262
  10. Fly Palermo Airport to Perugia Sant'Egidio Airport, bus

    1. Fly from Palermo Airport (PMO) to Perugia Sant'Egidio Airport (PEG)planePMO - PEG
    2. Take the bus from Perugia to Sienabus
    5h 38m
    €99–366
  11. Train via Chiusi

    1. Take the train from Palermo Centrale to Roma TerminitrainIc
    2. Take the train from Roma Termini to Chiusi-Chianciano T.trainRe
    3. Take the train from Chiusi-Chianciano T. to SienatrainRe
    18h 1m
    €53–145

Sicily to Siena by train

Calendar7Weekly Trains
Duration17h 9mAverage Duration
Ticket€67Cheapest Price
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Questions & Answers

What companies run services between Sicily, Italy and Siena, Italy?

You can take a train from Palermo Notarbartolo to Siena via Palermo Centrale, Roma Termini, and Firenze S.M.N. in around 17h 9m. Alternatively, FlixBus operates a bus from Palermo to Siena once daily. Tickets cost €50–120 and the journey takes 16h 20m.

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