The average bus between Sheffield and Siena takes 41h 36m and the fastest bus takes 36h 52m. The bus service runs several times per day from Sheffield to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Sheffield and Siena. The earliest departure is at 4:34 AM at night, and the last departure from Sheffield is at 11:35 PM which arrives into Siena at 6:55 PM. All services require a transfer at Meadowhall Interchange/C2 and take an average of 41h 36m. The schedules shown below are for the next available departures.
Arrives next day




37h 52m • 4 changes
Arrives +2 days




45h 52m • 4 changes
Arrives next day




37h 52m • 4 changes
Arrives +2 days




45h 52m • 4 changes
Want to know about travelling from Sheffield to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Sheffield to Siena. However, there are services departing from Sheffield station and arriving at Siena station via London Victoria. The journey, including transfers, takes approximately 41h 36m.
Sheffield to Siena bus services, operated by First South Yorkshire, depart from Meadowhall Interchange/B1 station.
Sheffield to Siena bus services, operated by First South Yorkshire, arrive at Siena station.
The distance between Sheffield and Siena is 1,460.7 km. The road distance is 2,000 km.
You can take a bus from Castle Street/CG22 to Siena via Meadowhall Interchange/C2, Meadowhall Interchange/B1, London Victoria, Paris, Quai de Bercy (Bercy Seine), Paris - Bercy-Seine Bus Station, and Florence Villa Constanza Bus Station in around 33h 46m.