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Santander to Siena buses

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Trip Overview

The bus between Santander and Siena takes 44h 10m. The bus runs, on average, 2 times per week from Santander to Siena. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

44h 10m
Duration
1,777 km
Distance
€193
Average price
Twice a week
Frequency

Santander to Siena bus times

Buses run twice a week between Santander and Siena. The service departs Santander at 5:50 PM in the evening, which arrives into Siena at 15:00:00. All services require a transfer at Bordeaux and take an average of 44h 10m. The schedules shown below are for the next available departures.

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusFlixBus44h 10m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusFlixBus44h 10m • 2 changes

Frequently asked questions

Want to know about travelling from Santander to Siena? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Siena.ExpandLaunch map view
  • Distance: 1,777.1 km
  • Duration: 44h 10m

What companies run services between Santander, Spain and Siena, Italy?

You can take a bus from Estación de autobuses de Santander to Siena via Bordeaux and Florence Villa Constanza Bus Station in around 26h 5m.

Operators