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Santander to Mainz buses

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Trip Overview

The average bus between Santander and Mainz takes 29h 27m and the fastest bus takes 27h 20m. The bus runs, on average, 4 times per week from Santander to Mainz. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

29h 27m
Duration
1,532 km
Distance
€158
Average price
4 times a week
Frequency

Santander to Mainz bus times

Buses run 4 times a week between Santander and Mainz. The service departs Santander at 5:50 PM in the evening, which arrives into Mainz at 22:10:00. All services require a transfer at Paris and take an average of 29h 27m. The schedules shown below are for the next available departures.

Departing Saturday, October 31, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus27h 20m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus27h 20m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBus35h 50m • 1 change

Departing Thursday, November 5, 2026

  •  → 

    Arrives next day

    FlixBusFlixBus27h 20m • 1 change

Frequently asked questions

Want to know about travelling from Santander to Mainz? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Santander to Mainz.ExpandLaunch map view
  • Distance: 1,532.1 km
  • Duration: 29h 27m

What companies run services between Santander, Spain and Mainz, Germany?

You can take a bus from Estación de autobuses de Santander to Mainz central train station via Paris and Paris, Quai de Bercy (Bercy Seine) in around 21h 25m.

Operators