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How to get fromSantander to Mainzby plane, bus, train, or car

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There are 8 ways to get from Santander to Mainz by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Santander Airport

    best
    1. Fly from Santander Airport (SDR) to Frankfurt (FRA)plane plane SDR - FRA
    5h 9m
    €111–299

  2. Bus to Bilbao Airport, fly

    cheapest
    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Fly from Bilbao Airport (BIO) to Frankfurt (FRA)plane plane BIO - FRA
    7h 14m
    €102–249

  3. Bus, train

    1. Take the bus from Estación de autobuses de Santander to Bordeauxbus bus
    2. Take the train from Bordeaux St Jean to Strasbourgtrain train Tgv
    3. Take the train from Strasbourg to Mannheim Hbftrain train Ice / ...
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    16h 27m
    €238–424

  4. Bus

    1. Take the bus from Estación de autobuses de Santander to Parisbus bus FlixBus 783
    2. Take the bus from Paris, Quai de Bercy (Bercy Seine) to Mainz central train stationbus bus N90 / ...
    21h 25m
    €128–194

  5. Drive  1,483.4 km

    1. Drive from Santander to Mainzcar car 1,483.4 km
    14h 54m
    €239–345

  6. Bus, train via Irun

    1. Take the bus from Estación de autobuses de Santander to Estación de Autobuses Donostia-San Sebastiánbus bus
    2. Take the train from Hendaye to Bordeaux St Jeantrain train Ter
    3. Take the train from Bordeaux St Jean to Strasbourgtrain train Tgv
    4. Take the train from Strasbourg to Mannheim Hbftrain train Ice / ...
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    17h 44m
    €261–475

  7. Train, bus

    1. Take the train from Santander to Basurto Hospitaltrain train
    2. Take the bus from Bilbao Intermodal to Saint-Jean-de-Luzbus bus
    3. Take the train from St Jean De Luz Ciboure to Massy Tgvtrain train Tgv
    4. Take the train from Paris Est to Mannheim Hbftrain train Ice
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train S5 / ...
    17h 58m
    €259–468

  8. Bus, train #2

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Luxembourgbus bus
    3. Take the bus from Luxembourg to Saarbrücken Hbfbus bus L40
    4. Take the train from Saarbrücken Hbf to Mainz, Römisches Theatertrain train Re3
    26h 14m

Santander to Mainz by bus, foot, and train

Calendar7Weekly Services
Duration16h 27mAverage Duration
Ticket€238Cheapest Price
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Questions & Answers

Map of how to get from Santander to Mainz.ExpandLaunch map view
  • Distance: 1,221.8 km
  • Duration: 5h 9m

What companies run services between Santander, Spain and Mainz, Germany?

Iberia, Vueling Airlines, and four other airlines fly from Santander Airport (SDR) to Frankfurt (FRA) 5 times a day. Alternatively, you can take a bus from Estación de autobuses de Santander to Mainz central train station via Paris and Paris, Quai de Bercy (Bercy Seine) in around 21h 25m.

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Train operators
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