There are 10 ways to get from Santander to Mainz by plane, bus, train, car, or train (Renfe)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Santander Airport to Frankfurt
best- Fly from Santander Airport (SDR) to Frankfurt (FRA)SDR - FRA
4h 49m€149–274Bus, train via Paris
cheapest- Take the bus from Santander E.A. to Bilbao Intermodal
- Take the bus from Bilbao Intermodal to Paris, Quai de Bercy
- Take the bus from Paris Bercy Seine Bus Stop to Kaiserslautern Bus Station
- Take the train from Kaiserslautern, Hbf to Bad Kreuznach, Bahnhof
- Take the train from Bad Kreuznach, Bahnhof to Mainz, HauptbahnhofRe3
26h 29m€55–185Bus, train
- Take the bus from Santander to Bordeaux
- Take the train from Bordeaux St Jean to StrasbourgTgv
- Take the train from Strasbourg Bahnhof to Mannheim, Hauptbahnhof82 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
16h 32m€175–577Bus
- Take the bus from Santander E.A. to Bilbao Intermodal
- Take the bus from Bilbao to Luxembourg
- Take the bus from Luxembourg, P+R Bouillon to Mainz central train station335
24h 15mDrive 1,482.7 km
- Drive from Santander to Mainz1,482.7 km
14h 46m€231–334Fly Santander Airport to Hahn, bus
- Fly from Santander Airport (SDR) to Hahn (HHN)SDR - HHN
- Take the bus from Frankfurt Hahn Airport to Mainz Short-term parking lot Am Schlag
6h 35m€106–325Bus to Bilbao Airport, fly to Frankfurt
- Take the bus from Santander E.A. to Bilbao Intermodal
- Fly from Bilbao Airport (BIO) to Frankfurt (FRA)BIO - FRA
6h 51m€111–271Fly Santander Airport to Cologne Bonn Airport, train
- Fly from Santander Airport (SDR) to Cologne Bonn Airport (CGN)SDR - CGN
- Take the train from Siegburg Bf to Frankfurt
6h 29m€121–361Bus, train via Irun
- Take the bus from Santander E.A. to Irun
- Take the train from Hendaye to Bordeaux St JeanTer
- Take the train from Bordeaux St Jean to StrasbourgTgv
- Take the train from Strasbourg Bahnhof to Mannheim, Hauptbahnhof82 / ...
- Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheaterS5 / ...
17h 44m€196–644Train
- Take the train from Santander to Madrid ChamartínAlv / ...
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgv
- Take the train from Avignon TGV to Frankfurt84
22h 6m€259–367
Santander to Mainz by bus, foot, and train
Questions & Answers
The cheapest way to get from Santander to Mainz is to bus and train via Paris which costs €55 - €190 and takes 26h 29m.
The fastest way to get from Santander to Mainz is to fly which takes 4h 49m and costs €140 - €280.
No, there is no direct bus from Santander to Mainz station. However, there are services departing from Santander E.A. and arriving at Mainz central train station via Bilbao and Luxembourg, P+R Bouillon. The journey, including transfers, takes approximately 24h 15m.
No, there is no direct train from Santander to Mainz. However, there are services departing from Santander and arriving at Mainz, Römisches Theater via Madrid Chamartín, Madrid-Puerta de Atocha-Almudena Grandes, Avignon TGV and Frankfurt. The journey, including transfers, takes approximately 22h 6m.
The distance between Santander and Mainz is 1222 km. The road distance is 1482.7 km.
The best way to get from Santander to Mainz without a car is to bus and train which takes 16h 32m and costs €170 - €600.
It takes approximately 4h 49m to get from Santander to Mainz, including transfers.
Santander to Mainz bus services, operated by ALSA, depart from Santander E.A. station.
Santander to Mainz train services, operated by Renfe Viajeros, depart from Santander station.
The best way to get from Santander to Mainz is to fly which takes 4h 49m and costs €140 - €280. Alternatively, you can bus, which costs and takes 24h 15m, you could also train, which costs €250 - €370 and takes 22h 6m.
What companies run services between Santander, Spain and Mainz, Germany?
Iberia, Vueling Airlines, and three other airlines fly from Santander Airport (SDR) to Frankfurt (FRA) 3 times a day. Alternatively, you can take a bus from Santander E.A. to Mainz central train station via Bilbao and Luxembourg, P+R Bouillon in around 24h 15m.
- Website
- ryanair.com
Flights from Santander Airport to Hahn via London Stansted
- Ave. Duration
- 5h 13m
- When
- Monday, Tuesday, and Thursday
- Estimated price
- €85–320
Flights from Santander Airport to Hahn via Valencia
- Ave. Duration
- 5h 25m
- When
- Sunday
- Estimated price
- €95–320
Flights from Santander Airport to Hahn via Palma Mallorca
- Ave. Duration
- 4h 30m
- When
- Monday
- Estimated price
- €95–320
Flights from Santander Airport to Hahn via Barcelona
- Ave. Duration
- 6h 30m
- When
- Monday, Thursday, and Saturday
- Estimated price
- €90–310
Flights from Santander Airport to Cologne Bonn Airport via London Stansted
- Ave. Duration
- 4h 15m
- When
- Monday and Thursday
- Estimated price
- €75–270
Flights from Santander Airport to Cologne Bonn Airport via Barcelona
- Ave. Duration
- 6h 35m
- When
- Tuesday
- Estimated price
- €75–270
- Website
- lufthansa.com
Flights from Santander Airport to Frankfurt via Manchester
- Ave. Duration
- 4h 35m
- When
- Monday
- Estimated price
- €80–270
Flights from Santander Airport to Frankfurt via Valencia
- Ave. Duration
- 6h 45m
- When
- Wednesday, Friday, and Sunday
- Estimated price
- €110–420
Flights from Bilbao Airport to Frankfurt
- Ave. Duration
- 2h 10m
- When
- Every day
- Estimated price
- €100–220
- Website
- iberia.com
Flights from Santander Airport to Frankfurt via Madrid
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- €80–310
- Website
- eurowings.com
Flights from Santander Airport to Cologne Bonn Airport via Palma Mallorca
- Ave. Duration
- 5h 5m
- When
- Monday
- Estimated price
- €95–370
Flights from Santander Airport to Cologne Bonn Airport via Menorca
- Ave. Duration
- 6h 10m
- When
- Tuesday and Saturday
- Estimated price
- €95–370
- Website
- condor.com
Flights from Santander Airport to Frankfurt via Barcelona
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- €85–300
- Website
- swiss.com
Flights from Bilbao Airport to Frankfurt via Zurich
- Ave. Duration
- 3h 55m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €180–420
- Website
- brusselsairlines.com
Flights from Bilbao Airport to Frankfurt via Brussels
- Ave. Duration
- 5h 5m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- €60–230
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Bordeaux St Jean to Strasbourg
- Ave. Duration
- 5h 40m
- Frequency
- Once daily
- Estimated price
- €110–250
- Website
- https://www.sncf-connect.com/en-en
Train from Strasbourg Bahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 23m
- Frequency
- Twice daily
- Estimated price
- €30–65
- Website
- https://www.sncf-connect.com/en-en
Train from Hendaye to Bordeaux St Jean
- Ave. Duration
- 2h 35m
- Frequency
- 4 times a day
- Estimated price
- €26–45
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Strasbourg Bahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 4m
- Frequency
- Every 4 hours
- Estimated price
- €30–65
- Website
- https://int.bahn.de/en
Train from Siegburg Bf to Frankfurt
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Estimated price
- €25–65
- Website
- https://int.bahn.de/en
Train from Avignon TGV to Frankfurt
- Ave. Duration
- 7h 12m
- Frequency
- 4 times a week
- Estimated price
- €130–150
- Website
- https://int.bahn.de/en
- Phone
- +43 51717
- Website
- nightjet.com
Train from Strasbourg Bahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 2h 25m
- Frequency
- Once a week
- Estimated price
- €28–260
- Website
- https://www.nightjet.com/en/#/home
- Sleeper Carriage
- €255–260
- Couchette Carriage
- €120–150
- Seating Carriage
- €28–35
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 1h 17m
- Frequency
- Every 30 minutes
- Estimated price
- €13–19
- Website
- https://int.bahn.de/en
Train from Kaiserslautern, Hbf to Bad Kreuznach, Bahnhof
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- €12–18
- Website
- https://int.bahn.de/en
Train from Bad Kreuznach, Bahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 29 min
- Frequency
- Twice daily
- Estimated price
- €10–15
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mannheim, Hauptbahnhof to Mainz, Römisches Theater
- Ave. Duration
- 57 min
- Frequency
- 6 times a week
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Hendaye to Bordeaux St Jean
- Ave. Duration
- 2h 38m
- Frequency
- Every 4 hours
- Estimated price
- €35–85
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- 2nd Class
- €35–60
- Rail 1st Class
- €60–85
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Santander to Madrid Chamartín
- Ave. Duration
- 4h 14m
- Frequency
- Twice daily
- Estimated price
- €30–85
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgv
- Ave. Duration
- 7h 37m
- Frequency
- Once daily
- Estimated price
- €85–120
- Website
- https://www.renfe.com/es/en
- Phone
- +49 6731 999 27-27
- info@vlexx.de
- Website
- vlexx.de
Train from Kaiserslautern, Hbf to Bad Kreuznach, Bahnhof
- Ave. Duration
- 55 min
- Frequency
- Every 4 hours
- Estimated price
- €12–18
- Schedules at
- vlexx.de
Train from Bad Kreuznach, Bahnhof to Mainz, Hauptbahnhof
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- €9–14
- Schedules at
- vlexx.de
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Santander to Bordeaux
- Ave. Duration
- 6h 5m
- Frequency
- Once daily
- Estimated price
- €24–50
- Website
- https://www.flixbus.co.uk
Bus from Luxembourg, P+R Bouillon to Mainz central train station
- Ave. Duration
- 2h 30m
- Frequency
- Twice daily
- Estimated price
- €13–27
- Website
- https://www.flixbus.co.uk
- Phone
- +34 910 207 007
- alsa@alsa.es
- Website
- alsa.com
Bus from Santander E.A. to Bilbao Intermodal
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €8–15
- Website
- https://www.alsa.com/en/
Bus from Santander E.A. to Irun
- Ave. Duration
- 3h 20m
- Frequency
- Every 4 hours
- Estimated price
- €17–27
- Website
- https://www.alsa.com/en/
Bus from Bilbao Intermodal to Paris, Quai de Bercy
- Ave. Duration
- 13h
- Frequency
- Once daily
- Estimated price
- €35–110
- Website
- https://www.alsa.com/en/
- Website
- blablacar.co.uk
Bus from Bilbao to Luxembourg
- Ave. Duration
- 18h 15m
- Frequency
- Once daily
- Schedules at
- blablacar.co.uk
- info@flibco.com
- Website
- flibco.com
Bus from Frankfurt Hahn Airport to Mainz Short-term parking lot Am Schlag
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €17–20
- Website
- https://www.flibco.com/en
- Phone
- +351 21 75 24 524
- Website
- rede-expressos.pt
Bus from Bilbao Intermodal to Paris, Quai de Bercy
- Ave. Duration
- 15h 15m
- Frequency
- 3 times a week
- Estimated price
- €8–105
- Website
- https://rede-expressos.pt/en
- Online ticket
- €8–45
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Paris Bercy Seine Bus Stop to Kaiserslautern Bus Station
- Ave. Duration
- 7h 45m
- Frequency
- Twice a week
- Estimated price
- €18–27
- Website
- https://union-ivkoni.com/en
Want to know more about travelling around Germany
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
5 delightfully under-the-radar French towns you need to visit
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
More Questions & Answers
Santander to Mainz bus services, operated by ALSA, arrive at Bilbao Intermodal station.
Santander to Mainz train services, operated by Renfe Viajeros, arrive at Madrid Chamartín station.
Yes, the driving distance between Santander to Mainz is 1483 km. It takes approximately 14h 46m to drive from Santander to Mainz.
Book your Santander to Mainz bus tickets online with Omio.
There are 1153+ hotels available in Mainz.

























































