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How to get fromSantander to Mainzby plane, bus, train, car, or train (Renfe, TGV)

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There are 8 ways to get from Santander to Mainz by plane, bus, train, car, or train (Renfe, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Santander Airport

    best
    1. Fly from Santander Airport (SDR) to Frankfurt (FRA)plane plane SDR - FRA
    5h 23m
    €102–237

  2. Bus, train via Antony

    1. Take the bus from Estación de autobuses de Santander to Estación de Autobuses Donostia-San Sebastiánbus bus
    2. Take the train from Hendaye to Massy Tgvtrain train Tgv
    3. Take the train from Massy Tgv to Mannheim Hbftrain train Tgv
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train 55 / ...
    15h 20m
    €300–536

  3. Bus

    1. Take the bus from Estación de autobuses de Santander to Parisbus bus FlixBus 783
    2. Take the bus from Paris, Quai de Bercy (Bercy Seine) to Mainz central train stationbus bus N90 / ...
    21h 25m
    €120–207

  4. Drive 1,483.4 km

    1. Drive from Santander to Mainzcar car 1,483.4 km
    14h 54m
    €237–342

  5. Bus to Bilbao Airport, fly

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Fly from Bilbao Airport (BIO) to Frankfurt (FRA)plane plane BIO - FRA
    7h 42m
    €104–242

  6. Bus, train

    1. Take the bus from Estación de autobuses de Santander to Bordeauxbus bus FlixBus 783
    2. Take the train from Bordeaux St Jean to Frankfurt(Main)Hbftrain train Tgv
    15h 36m
    €302–492

  7. Train

    1. Take the train from Santander to Bilbaotrain train
    2. Take the train from Zazpikaleak/Casco Viejo-Bilbao to Amara-Donostiatrain train E1
    3. Take the train from St Jean De Luz Ciboure to Bordeaux St Jeantrain train Ter
    4. Take the train from Bordeaux St Jean to Mannheim Hbftrain train Tgv
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Hauptbahnhoftrain train 55 / ...
    20h 10m
    €293–532

  8. Bus, train #2

    1. Take the bus from Estación de autobuses de Santander to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao Intermodal to Metz - Bus Stationbus bus
    3. Take the bus from Metz Ville to Saarbrücken Hbfbus bus Bus
    4. Take the train from Saarbrücken Hbf to Mainz, Römisches Theatertrain train Re3
    26h 48m

Santander to Mainz by bus, foot, and train

Calendar1Weekly Services
Duration15h 20mAverage Duration
Ticket€300Cheapest Price
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Questions & Answers

Map of how to get from Santander to Mainz.ExpandLaunch map view
  • Distance: 1,221.8 km
  • Duration: 5h 23m

What companies run services between Santander, Spain and Mainz, Germany?

Iberia, Ryanair, and three other airlines fly from Santander Airport (SDR) to Frankfurt (FRA) 5 times a day. Alternatively, you can take a bus from Estación de autobuses de Santander to Mainz central train station via Paris and Paris, Quai de Bercy (Bercy Seine) in around 21h 25m.

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Train operators
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