Rome2Rio

How to get fromSantander to Mainzby plane, bus, train, car, night train or train (Renfe, TGV)

Find Transport to Mainz

See all options

There are 9 ways to get from Santander to Mainz by plane, bus, train, car, night train, or train (Renfe, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Santander Airport to Frankfurt

    best
    1. Fly from Santander Airport (SDR) to Frankfurt (FRA)planeSDR - FRA
    4h 47m
    €150–271
  2. Bus

    cheapest
    1. Take the bus from Santander to ParisbusFlixBus 783 / ...
    2. Take the bus from Paris, Quai de Bercy (Bercy Seine) to Mainz central train stationbusN90 / ...
    21h 35m
    €71–179
  3. Bus, train

    1. Take the bus from Santander E.A. to Irunbus
    2. Take the train from Hendaye to Massy TgvtrainTgv
    3. Take the train from Paris Est to Mannheim HbftrainIce
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches TheatertrainS6
    15h 46m
    €151–555
  4. Drive 1,482.7 km

    1. Drive from Santander to Mainzcar1,482.7 km
    14h 46m
    €234–338
  5. Bus to Bilbao Airport, fly to Frankfurt

    1. Take the bus from Santander E.A. to Bilbao Intermodalbus
    2. Fly from Bilbao Airport (BIO) to Frankfurt (FRA)planeBIO - FRA
    6h 49m
    €111–260
  6. Fly Santander Airport to Hahn, bus

    1. Fly from Santander Airport (SDR) to Hahn (HHN)planeSDR - HHN
    2. Take the bus from Frankfurt Hahn Airport to Mainz Short-term parking lot Am Schlagbus
    8h 45m
    €115–352
  7. Bus, train, night train

    1. Take the bus from Santander to Bordeauxbus
    2. Take the train from Bordeaux St Jean to StrasbourgtrainTgv
    3. Take the night train from Strasbourg to Mainz HbfnighttrainNj
    16h 47m
    €173–581
  8. Train

    1. Take the train from Santander to Madrid ChamartíntrainAlv / ...
    2. Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Avignon Tgvtrain
    3. Take the train from Avignon Tgv to Frankfurt(Main)HbftrainTgv
    22h 2m
    €197–487
  9. Bus, night train

    1. Take the bus from Santander E.A. to Bilbao Intermodalbus
    2. Take the bus from Bilbao Intermodal to Brussels - Midi Train Stationbus
    3. Take the night train from Brussel-Zuid / Bruxelles-Midi to Mainz HbfnighttrainNj
    28h 11m
    €73–395

Santander to Mainz by bus, train, and foot

Calendar9Weekly Services
Duration15h 46mAverage Duration
Ticket€151Cheapest Price
See schedules

Questions & Answers

What companies run services between Santander, Spain and Mainz, Germany?

Iberia, Vueling Airlines, and three other airlines fly from Santander Airport (SDR) to Frankfurt (FRA) 3 times a day. Alternatively, you can take a bus from Santander to Mainz central train station via Paris and Paris, Quai de Bercy (Bercy Seine) in around 21h 35m.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Train operators
Bus operators

Want to know more about travelling around Germany

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers