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How to get fromSantander to Mainzby plane, bus, train, car or train (Renfe, TGV)

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There are 9 ways to get from Santander to Mainz by plane, bus, train, car, or train (Renfe, TGV)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Santander Airport to Frankfurt

    best
    1. Fly from Santander Airport (SDR) to Frankfurt (FRA)plane plane SDR - FRA
    5h 17m
    €143–363

  2. Fly Santander Airport to Hahn, bus

    cheapest
    1. Fly from Santander Airport (SDR) to Hahn (HHN)plane plane SDR - HHN
    2. Take the bus from Hahn to Mainz, Hauptbahnhofbus bus
    6h 35m
    €87–285

  3. Bus, train

    1. Take the bus from Santander to Bordeauxbus bus FlixBus 783
    2. Take the train from Bordeaux St Jean to Frankfurt(Main)Hbftrain train Tgv
    15h 43m
    €267–445

  4. Bus

    1. Take the bus from Santander to Parisbus bus FlixBus 783
    2. Take the bus from Paris, Quai de Bercy (Bercy Seine) to Mainz central train stationbus bus N90 / ...
    21h 35m
    €101–179

  5. Drive 1,482.7 km

    1. Drive from Santander to Mainzcar car 1,482.7 km
    14h 55m
    €237–342

  6. Bus to Bilbao Airport, fly to Frankfurt

    1. Take the bus from Santander E.A. to Bilbao Intermodalbus bus
    2. Fly from Bilbao Airport (BIO) to Frankfurt (FRA)plane plane BIO - FRA
    6h 55m
    €111–272

  7. Bus, train via Antony

    1. Take the bus from Santander E.A. to Estación de Autobuses Donostia-San Sebastiánbus bus
    2. Take the train from Hendaye to Massy Tgvtrain train Tgv
    3. Take the train from Massy Tgv to Mannheim Hbftrain train Tgv
    4. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    16h 10m
    €272–471

  8. Train

    1. Take the train from Santander to Bilbaotrain train
    2. Take the train from Zazpikaleak/Casco Viejo-Bilbao to Amara-Donostiatrain train E1
    3. Take the train from Hendaye to Bordeaux St Jeantrain train Ter
    4. Take the train from Bordeaux St Jean to Mannheim Hbftrain train Tgv
    5. Take the train from Mannheim, Hauptbahnhof to Mainz, Römisches Theatertrain train S5 / ...
    20h 44m
    €260–472

  9. Bus, train #2

    1. Take the bus from Santander E.A. to Bilbao Intermodalbus bus
    2. Take the bus from Bilbao to Luxembourgbus bus
    3. Take the bus from Luxembourg, Gare Centrale routière to Saarbrücken, Hauptbahnhofbus bus L40
    4. Take the train from Saarbrücken Hbf to Mainz, Römisches Theatertrain train Re3
    26h 32m

Santander to Mainz by bus, foot, and train

Calendar1Weekly Services
Duration15h 43mAverage Duration
Ticket€267Cheapest Price
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Questions & Answers

What companies run services between Santander, Spain and Mainz, Germany?

Iberia, Ryanair, and four other airlines fly from Santander Airport (SDR) to Frankfurt (FRA) 4 times a day. Alternatively, you can take a bus from Santander to Mainz central train station via Paris and Paris, Quai de Bercy (Bercy Seine) in around 21h 35m.

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Train operators
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