The bus between Prague and Rome takes 21h. There is at least one bus per day from Prague to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Prague and Rome. The earliest departure is at 5:45 PM in the evening, and the last departure from Prague is at 5:45 PM which arrives into Rome at 2:45 PM. All services run direct with no transfers required, and take on average 21h. The schedules shown below are for the next available departures.
Want to know about travelling from Prague to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Prague station and arriving at Rome station. Services depart once daily, and operate Once daily. The journey takes approximately 21h.
Prague to Rome bus services, operated by FlixBus, depart from Praha, Hlavní Nádraží station.
Prague to Rome bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
Book your Prague to Rome bus tickets online with FlixBus.
The distance between Prague and Rome is 922.2 km. The road distance is 1,411 km.
FlixBus operates a bus from Praha, Hlavní Nádraží to Roma, Autostazione Tiburtina once daily. Tickets cost €95–170 and the journey takes 21h.