The average bus between Rome and Palermo takes 12h 45m and the fastest bus takes 11h 45m. The bus service runs several times per day from Rome to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Rome and Palermo. The earliest departure is at 1:20 AM at night, and the last departure from Rome is at 8:00 PM which arrives into Palermo at 7:45 AM. All services run direct with no transfers required, and take on average 12h 45m. The schedules shown below are for the next available departures.
Want to know about travelling from Rome to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Rome station and arriving at Palermo station. Services depart twice daily, and operate Twice daily. The journey takes approximately 12h 45m.
Rome to Palermo bus services, operated by Autoservizi Salemi Srl, depart from Roma, Autostazione Tiburtina station.
Rome to Palermo bus services, operated by Autoservizi Salemi Srl, arrive at Palermo Terminal Bus station.
Book your Rome to Palermo bus tickets online with Autoservizi Salemi Srl and FlixBus.
The distance between Rome and Palermo is 425.1 km. The road distance is 951 km.
Autoservizi Salemi Srl operates a bus from Roma, Autostazione Tiburtina to Palermo Terminal Bus twice daily. Tickets cost €35–55 and the journey takes 11h 45m. FlixBus also services this route once daily.