Bus Rome to Milan from €45 | Tickets & Timetables

Trip Overview

The average bus between Rome and Milan takes 8h 5m and the fastest bus takes 7h. The bus service runs several times per day from Rome to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 5m
Duration: 567 km
Distance: €45
Average price: Every 4 hours
Frequency

Bus via Florence

best

Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus 510 / ...
Take the bus from Florence Villa Constanza Bus Station to Milano, San Donato M3bus N528 / ...

7h 40m

€33–71

Rome to Milan bus times

Buses run every 4 hours between Rome and Milan. The earliest departure is at 6:30 AM in the morning, and the last departure from Rome is at 10:55 PM which arrives into Milan at 7:50 AM. All services require a transfer, and take on average 8h 5m. The schedules shown below are for the next available departures.

Departing Thursday, April 30, 2026

6:30 AM → 2:35 PM
8h 5m • 1 change
10:40 AM → 6:30 PM
7h 50m • 1 change
12:20 PM → 8:55 PM
8h 35m • 1 change
2:45 PM → 9:55 PM
7h 10m • 1 change
Show more

Departing Friday, May 1, 2026

6:30 AM → 2:35 PM
8h 5m • 1 change
10:40 AM → 6:30 PM
7h 50m • 1 change
12:20 PM → 8:55 PM
8h 35m • 1 change
4:00 PM → 11:00 PM
7h • 1 change
Show more

Departing Saturday, May 2, 2026

6:30 AM → 2:35 PM
8h 5m • 1 change
10:40 AM → 6:30 PM
7h 50m • 1 change
12:20 PM → 8:55 PM
8h 35m • 1 change
4:00 PM → 11:00 PM
7h • 1 change
Show more

Departing Sunday, May 3, 2026

6:30 AM → 2:35 PM
8h 5m • 1 change
10:40 AM → 6:30 PM
7h 50m • 1 change
12:20 PM → 8:55 PM
8h 35m • 1 change
2:45 PM → 9:55 PM
7h 10m • 1 change
Show more

Departing Monday, May 4, 2026

6:30 AM → 2:35 PM
8h 5m • 1 change
10:40 AM → 6:30 PM
7h 50m • 1 change
12:20 PM → 8:55 PM
8h 35m • 1 change
4:00 PM → 11:00 PM
7h • 1 change
Show more

Departing Tuesday, May 5, 2026

6:30 AM → 2:35 PM
8h 5m • 1 change
10:40 AM → 6:30 PM
7h 50m • 1 change
2:45 PM → 10:20 PM
7h 35m • 1 change
9:45 PM → 5:15 AM
Arrives next day
7h 30m • 1 change
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Departing Wednesday, May 6, 2026

10:40 AM → 6:30 PM
7h 50m • 1 change
12:10 PM → 9:55 PM
9h 45m • 1 change
9:45 PM → 5:15 AM
Arrives next day
7h 30m • 1 change

Frequently asked questions

Want to know about travelling from Rome to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.