The average bus between Pisa and Lazio takes 5h 33m and the fastest bus takes 4h 56m. The bus service runs several times per day from Pisa to Lazio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Pisa and Lazio. The earliest departure is at 12:25 AM at night, and the last departure from Pisa is at 10:00 PM which arrives into Lazio at 2:56 AM. All services require a transfer, and take on average 5h 33m. The schedules shown below are for the next available departures.

5h 27m • 1 change
5h 36m • 1 changeArrives next day

4h 56m • 1 change
5h 53m • 1 change
5h 27m • 1 change
5h 41m • 1 change
5h 36m • 1 change
6h 6m • 1 change
5h 27m • 1 change
5h 40m • 1 change
5h 46m • 1 change
6h 12m • 1 change
5h 15m • 1 change
5h 40m • 1 change
5h 46m • 1 change
5h 53m • 1 change
5h 27m • 1 change
5h 41m • 1 change
5h 36m • 1 changeWant to know about travelling from Pisa to Lazio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Pisa to Lazio. However, there are services departing from Pisa station and arriving at Lazio station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 5h 33m.
Pisa to Lazio bus services, operated by FlixBus, depart from Pisa station.
Pisa to Lazio bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Pisa and Lazio is 272 km. The road distance is 341 km.
FlixBus operates a bus from Pisa to Roma, Autostazione Tiburtina 3 times a day. Tickets cost €27–45 and the journey takes 4h 45m.