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How to get fromPalermo to Madridby plane, train (Trenitalia, Renfe, Ouigo), ferry, train, bus or shuttle

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There are 7 ways to get from Palermo to Madrid by plane, train (Trenitalia, Renfe, Ouigo), ferry, train, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Palermo Airport

    best
    1. Fly from Palermo Airport (PMO) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane PMO - MAD
    5h 45m
    €60–198

  2. Train

    1. Take the train from Palermo Centrale to Roma Terminitrain train Ic
    2. Take the train from Roma Termini to Milano Centraletrain train
    3. Take the train from Milano Centrale to Lyon Part Dieutrain train Fr
    4. Take the train from Lyon Part Dieu to Barcelona-Santstrain train
    5. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    29h 44m
    €261–493

  3. Ferry, train

    1. Take the ferry from Port of Palermo to Port of Civitavecchiaferry ferry
    2. Take the ferry from Port of Civitavecchia to Port de Barcelonaferry ferry
    3. Take the train from Barcelona-Sants to Madrid-Puerta de Atocha-Almudena Grandestrain train Ave
    36h 37m
    €123–246

  4. Bus

    1. Take the bus from Palermo to Roma, Autostazione Tiburtinabus bus
    2. Take the bus from Roma, Autostazione Tiburtina to Barcelona - North Bus Stationbus bus
    3. Take the bus from Barcelona, Estació d'Autobusos Nord to Madrid, Avenida de Américabus bus
    44h 10m
    €170–326

  5. Shuttle to Trapani Airport, fly

    1. Take a shuttle bus from Lazio Municipio to Trapani Birgi Airportshuttle bus
    2. Fly from Trapani Airport (TPS) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane TPS - MAD
    9h 10m
    €82–234

  6. Train to Catania–Fontanarossa Airport, fly

    1. Take the train from Palermo Centrale to Catania Centraletrain train
    2. Fly from Catania–Fontanarossa Airport (CTA) to Adolfo Suárez Madrid–Barajas Airport (MAD)plane plane CTA - MAD
    8h 45m
    €72–228

  7. Bus via Turin

    1. Take the bus from Palermo to Turinbus bus
    2. Take the bus from Turin to Lyonbus bus 480 / ...
    3. Take the bus from Lyon to Madridbus bus
    2d
    €208–358

Palermo to Madrid by bus

Calendar14Weekly Buses
Duration44h 10mAverage Duration
Ticket€170Cheapest Price
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Questions & Answers

What companies run services between Palermo, Italy and Madrid, Spain?

Iberia, Ryanair, and Vueling Airlines fly from Palermo Airport (PMO) to Adolfo Suárez Madrid–Barajas Airport (MAD) 3 times a day. Alternatively, you can take a train from Palermo Centrale to Madrid-Puerta de Atocha-Almudena Grandes via Roma Termini, Milano Centrale, Lyon Part Dieu, and Barcelona-Sants in around 29h 44m.

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