The average bus between Omaha and St. Louis takes 12h 37m and the fastest bus takes 12h 10m. The bus service runs several times per day from Omaha to St. Louis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Omaha and St. Louis. The earliest departure is at 6:55 PM in the evening, and the last departure from Omaha is at 11:55 PM which arrives into St. Louis at 12:05 PM. All services require a transfer, and take on average 12h 37m. The schedules shown below are for the next available departures.
Arrives next day

13h 5m • 1 change
Arrives next day

12h 10m • 1 change
Arrives next day

13h 5m • 1 change
Arrives next day

12h 10m • 1 change
Arrives next day

13h 5m • 1 change
Arrives next day

12h 10m • 1 change
Arrives next day

13h 5m • 1 change
Arrives next day

12h 10m • 1 change
Want to know about travelling from Omaha to St. Louis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Omaha to St. Louis. However, there are services departing from Omaha station and arriving at St. Louis station via Kansas City. The journey, including transfers, takes approximately 12h 37m.
Omaha to St. Louis bus services, operated by Jefferson Lines, depart from Omaha station.
Omaha to St. Louis bus services, operated by Jefferson Lines, arrive at St Louis Bus Station.
Book your Omaha to St. Louis bus tickets online with Jefferson Lines and Greyhound USA.
The distance between Omaha and St. Louis is 570 km. The road distance is 737 km.
You can take a bus from Omaha to St Louis Bus Station via Kansas City Bus Station in around 9h 20m.