The bus between Milan and Palermo takes 21h 55m. There is at least one bus per day from Milan to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Milan and Palermo. The earliest departure is at 1:05 PM in the afternoon, and the last departure from Milan is at 1:05 PM which arrives into Palermo at 11:00 AM. All services run direct with no transfers required, and take on average 21h 55m. The schedules shown below are for the next available departures.
Want to know about travelling from Milan to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Milan station and arriving at Palermo station. Services depart once daily, and operate Once daily. The journey takes approximately 21h 55m.
Milan to Palermo bus services, operated by FlixBus, depart from Milano, Autostazione Lampugnano station.
Milan to Palermo bus services, operated by FlixBus, arrive at Palermo station.
Book your Milan to Palermo bus tickets online with FlixBus.
The distance between Milan and Palermo is 884.5 km. The road distance is 1,592 km.
FlixBus operates a bus from Milano, Autostazione Lampugnano to Palermo once daily. Tickets cost €130–220 and the journey takes 21h 55m. Onebus also services this route once a week.