The average bus between Genoa and Palermo takes 22h 20m and the fastest bus takes 20h 55m. The bus service runs several times per day from Genoa to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Genoa and Palermo. The earliest departure is at 11:15 AM in the morning, and the last departure from Genoa is at 6:20 PM which arrives into Palermo at 3:15 PM. All services require a transfer, and take on average 22h 20m. The schedules shown below are for the next available departures.
Arrives next day

23h 45m • 1 change
Arrives next day

20h 55m • 1 change
Arrives next day

23h 45m • 1 change
Arrives next day

20h 55m • 1 change
Arrives next day

23h 45m • 1 change
Arrives next day

20h 55m • 1 change
Arrives next day

23h 45m • 1 change
Arrives next day

20h 55m • 1 change
Arrives next day

23h 45m • 1 change
Arrives next day

20h 55m • 1 change
Want to know about travelling from Genoa to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Genoa to Palermo. However, there are services departing from Genoa station and arriving at Palermo station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 22h 20m.
Genoa to Palermo bus services, operated by FlixBus, depart from Genoa station.
Genoa to Palermo bus services, operated by FlixBus, arrive at Palermo station.
Book your Genoa to Palermo bus tickets online with FlixBus.
The distance between Genoa and Palermo is 787.9 km. The road distance is 1,474 km.
You can take a bus from Genoa to Palermo via Florence Villa Constanza Bus Station in around 20h 40m.