The train between Milan and Palermo takes 22h 25m. There is at least one train per day from Milan to Palermo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run once daily between Milan and Palermo. The earliest departure is at 8:40 PM in the evening, and the last departure from Milan is at 8:40 PM which arrives into Palermo at 7:05 PM. All services require a transfer, and take on average 22h 25m. The schedules shown below are for the next available departures.
Want to know about travelling from Milan to Palermo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Palermo. However, there are services departing from Milan station and arriving at Palermo station via Roma Termini. The journey, including transfers, takes approximately 22h 25m.
Milan to Palermo train services, operated by ItaloTreno, depart from Milano Centrale station.
Milan to Palermo train services, operated by ItaloTreno, arrive at Palermo Centrale station.
Book your Milan to Palermo train tickets online with ItaloTreno and Trenitalia Intercity.
The distance between Milan and Palermo is 884.5 km. The road distance is 1,427 km.
You can take a train from Milano Centrale to Palermo Centrale via Roma Termini in around 15h 56m.