The average bus between Milan and Lazio takes 8h 14m and the fastest bus takes 7h 11m. The bus service runs several times per day from Milan to Lazio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Milan and Lazio. The earliest departure is at 1:10 AM at night, and the last departure from Milan is at 9:20 PM which arrives into Lazio at 6:31 AM. All services require a transfer at Florence Villa Constanza Bus Station and take an average of 8h 14m. The schedules shown below are for the next available departures.
Arrives next day


7h 46m • 2 changes
Arrives next day


9h 14m • 2 changes


8h • 2 changes


7h 27m • 2 changes


8h 19m • 2 changes


8h 16m • 2 changes


8h • 2 changes


8h 19m • 2 changes
Arrives next day


8h 11m • 2 changes
Arrives next day


9h 14m • 2 changes


8h • 2 changes


8h 19m • 2 changes


8h 12m • 2 changes


8h 10m • 2 changes


8h • 2 changes


7h 27m • 2 changes


8h 19m • 2 changes


8h 2m • 2 changes


8h • 2 changes


7h 27m • 2 changes


8h 19m • 2 changes


8h 2m • 2 changes


7h 54m • 2 changes


7h 11m • 2 changes


8h 7m • 2 changes


7h 45m • 2 changes
Want to know about travelling from Milan to Lazio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Milan to Lazio. However, there are services departing from Milan station and arriving at Lazio station via Florence Villa Constanza Bus Station station. The journey, including transfers, takes approximately 8h 14m.
Milan to Lazio bus services, operated by FlixBus, depart from Milano, San Donato M3 station.
Milan to Lazio bus services, operated by FlixBus, arrive at Roma, Autostazione Tiburtina station.
The distance between Milan and Lazio is 482.2 km. The road distance is 569 km.
You can take a bus from Milano, San Donato M3 to Termini via Florence Villa Constanza Bus Station and Roma, Autostazione Tiburtina in around 7h 33m.