The average bus between Matamoros and Tlaxcala takes 18h 15m and the fastest bus takes 17h 30m. The bus service runs several times per day from Matamoros to Tlaxcala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Matamoros and Tlaxcala. The earliest departure is at 4:10 PM in the afternoon, and the last departure from Matamoros is at 7:40 PM which arrives into Tlaxcala at 1:40 PM. All services require a transfer at México D.F., Central De Autobuses Del Norte and take an average of 18h 15m. The schedules shown below are for the next available departures.
Arrives next day



16h 30m • 3 changes
Arrives next day



18h • 3 changes
Arrives next day



16h 30m • 3 changes
Arrives next day



18h • 3 changes
Arrives next day



16h 30m • 3 changes
Arrives next day



18h • 3 changes
Arrives next day



16h 30m • 3 changes
Arrives next day



18h • 3 changes
Want to know about travelling from Matamoros to Tlaxcala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Matamoros to Tlaxcala. However, there are services departing from Matamoros station and arriving at Tlaxcala station via Terminal Central de Autobuses del Norte. The journey, including transfers, takes approximately 18h 15m.
Matamoros to Tlaxcala bus services, operated by ETN Turistar, depart from Matamoros station.
Matamoros to Tlaxcala bus services, operated by ETN Turistar, arrive at Tlaxcala station.
The distance between Matamoros and Tlaxcala is 733 km. The road distance is 1,033 km.
You can take a bus from Matamoros to Tlaxcala via México D.F., Central De Autobuses Del Norte, Av. 100 Metros - Frente a Metro Central Camionera, Teatro Blanquita, San Lázaro, and México TAPO in around 13h 44m.