The average bus between Cholula and Tlaxcala takes 1h 54m and the fastest bus takes 1h 5m. The bus service runs several times per day from Cholula to Tlaxcala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 3 hours between Cholula and Tlaxcala. The earliest departure is at 9:05 AM in the morning, and the last departure from Cholula is at 10:40 PM which arrives into Tlaxcala at 6:10 AM. All services require a transfer at Puebla, Central de Autobuses and take an average of 1h 54m. The schedules shown below are for the next available departures.

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1h 15m • 1 changeWant to know about travelling from Cholula to Tlaxcala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Cholula to Tlaxcala. However, there are services departing from Puebla station and arriving at Tlaxcala CATLA station via Puebla, Central de Autobuses station. The journey, including transfers, takes approximately 1h 54m.
Cholula to Tlaxcala bus services, operated by Flixbus USA, depart from Puebla station.
Cholula to Tlaxcala bus services, operated by Autobuses Valles, arrive at Tlaxcala CATLA station.
The distance between Cholula and Tlaxcala is 30.3 km. The road distance is 37 km.
You can take a bus from Puebla to Tlaxcala CATLA via Puebla, Central de Autobuses and Puebla CAPU in around 1h 22m.