Bus Cdmx to Tlaxcala from $240 | Tickets & Timetables

Trip Overview

The bus between Cdmx and Tlaxcala takes 2h 20m. There is a bus service every few hours from Cdmx to Tlaxcala. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 20m
Duration: 122 km
Distance: $240
Average price: Hourly
Frequency

Line 4 bus, bus

best

Take the bus from Plaza de la República to San Lázaro Orientebus 4
Take the bus from México TAPO to Tlaxcalabus Supra / ...

2h 34m

$56–360

Cdmx to Tlaxcala bus times

Buses run hourly between Cdmx and Tlaxcala. The earliest departure is at 5:19 AM in the morning, and the last departure from Cdmx is at 10:34 PM which arrives into Tlaxcala at 12:55 AM. All services require a transfer at San Lázaro Oriente and take an average of 2h 20m. The schedules shown below are for the next available departures.

Departing Friday, May 1, 2026

10:34 PM → 12:55 AM
Arrives next day
2h 20m • 1 change

Departing Saturday, May 2, 2026

5:19 AM → 7:40 AM
2h 20m • 1 change
6:19 AM → 8:40 AM
2h 20m • 1 change
7:19 AM → 9:40 AM
2h 20m • 1 change
8:49 AM → 11:10 AM
2h 20m • 1 change
Show more

Departing Sunday, May 3, 2026

5:19 AM → 7:40 AM
2h 20m • 1 change
6:19 AM → 8:40 AM
2h 20m • 1 change
7:19 AM → 9:40 AM
2h 20m • 1 change
8:49 AM → 11:10 AM
2h 20m • 1 change
Show more

Departing Monday, May 4, 2026

5:19 AM → 7:40 AM
2h 20m • 1 change
6:19 AM → 8:40 AM
2h 20m • 1 change
7:19 AM → 9:40 AM
2h 20m • 1 change
8:49 AM → 11:10 AM
2h 20m • 1 change
Show more

Departing Tuesday, May 5, 2026

5:19 AM → 7:40 AM
2h 20m • 1 change
6:19 AM → 8:40 AM
2h 20m • 1 change
7:19 AM → 9:40 AM
2h 20m • 1 change
8:49 AM → 11:10 AM
2h 20m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Cdmx to Tlaxcala? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.