The average bus between Manchester and Lyon takes 23h 9m and the fastest bus takes 19h 25m. The bus service runs several times per day from Manchester to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Manchester and Lyon. The earliest departure is at 2:50 AM at night, and the last departure from Manchester is at 11:59 PM which arrives into Lyon at 1:10 AM. All services require a transfer at London Victoria and take an average of 23h 9m. The schedules shown below are for the next available departures.
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24h 5m • 3 changes
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23h 51m • 3 changes
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26h 30m • 3 changes
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22h 15m • 3 changes
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27h 10m • 3 changes
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22h 20m • 3 changes
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22h 15m • 3 changes
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30h 10m • 3 changes
Arrives +2 days



25h 11m • 3 changes
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25h 55m • 3 changes
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23h 51m • 3 changes
Want to know about travelling from Manchester to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Lyon. However, there are services departing from Manchester station and arriving at Lyon station via London Victoria. The journey, including transfers, takes approximately 23h 9m.
Manchester to Lyon bus services, operated by FlixBus, depart from Manchester, Shudehill Interchange station.
Manchester to Lyon bus services, operated by FlixBus, arrive at Lyon station.
Book your Manchester to Lyon bus tickets online with FlixBus.
The distance between Manchester and Lyon is 998.8 km. The road distance is 1,242 km.
You can take a bus from Manchester, Shudehill Interchange to Lyon via London Victoria, Dover, and Paris, Quai de Bercy (Bercy Seine) in around 21h 19m.