The average bus between Manchester and Lyon takes 22h 28m and the fastest bus takes 20h 50m. The bus service runs several times per day from Manchester to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Manchester and Lyon. The earliest departure is at 2:50 AM at night, and the last departure from Manchester is at 11:59 PM which arrives into Lyon at 11:50 PM. All services require a transfer at London Victoria and take an average of 22h 28m. The schedules shown below are for the next available departures.
Arrives next day



22h 50m • 3 changes
Arrives next day



25h 10m • 3 changes
Arrives next day



23h 51m • 3 changes
Arrives next day



24h 40m • 3 changes
Arrives next day



21h 50m • 3 changes
Arrives next day



22h 50m • 3 changes
Arrives next day



25h 10m • 3 changes
Arrives next day



24h 40m • 3 changes
Arrives next day



21h 50m • 3 changes
Arrives next day



22h 50m • 3 changes
Arrives next day



25h 10m • 3 changes
Arrives next day



23h 30m • 3 changes
Arrives next day



21h 50m • 3 changes
Arrives next day



22h 50m • 3 changes
Arrives next day



25h 10m • 3 changes
Arrives next day



23h 30m • 3 changes
Arrives next day



22h 5m • 3 changes
Arrives next day



22h 50m • 3 changes
Arrives next day



25h 10m • 3 changes
Arrives next day



23h 30m • 3 changes
Arrives next day



22h 5m • 3 changes
Arrives next day



22h 50m • 3 changes
Arrives next day



22h 45m • 3 changes
Want to know about travelling from Manchester to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Lyon. However, there are services departing from Manchester station and arriving at Lyon station via London Victoria. The journey, including transfers, takes approximately 22h 28m.
Manchester to Lyon bus services, operated by FlixBus, depart from Manchester, Shudehill Interchange station.
Manchester to Lyon bus services, operated by FlixBus, arrive at Lyon - Gerland Bus Station.
Book your Manchester to Lyon bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Manchester and Lyon is 998.8 km. The road distance is 1,242 km.
You can take a bus from Manchester, Shudehill Interchange to Lyon - Gerland Bus Station via London Victoria, Dover, Paris, Quai de Bercy (Bercy Seine), and Paris - Bercy-Seine Bus Station in around 20h 18m.