The average train between Manchester and Lyon takes 10h 47m and the fastest train takes 7h 24m. The train service runs several times per day from Manchester to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Manchester and Lyon. The earliest departure is at 8:05 AM in the morning, and the last departure from Manchester is at 10:15 PM which arrives into Lyon at 2:00 PM. All services require a transfer at London Euston and take an average of 10h 47m. The schedules shown below are for the next available departures.


8h 54m • 2 changes


8h 26m • 2 changes
Arrives next day


17h 15m • 2 changes


8h 24m • 2 changes


8h 27m • 2 changes


9h 25m • 2 changes
Arrives next day


17h 15m • 2 changes


8h 24m • 2 changes


9h 27m • 2 changes


9h 25m • 2 changes
Arrives next day


17h 15m • 2 changes


8h 24m • 2 changes


9h 27m • 2 changes


9h 25m • 2 changes
Arrives next day


17h 15m • 2 changes


8h 24m • 2 changes


9h 27m • 2 changes


9h 25m • 2 changes
Arrives next day


17h 15m • 2 changes
Want to know about travelling from Manchester to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Manchester to Lyon. However, there are services departing from Manchester station and arriving at Lyon station via London Euston. The journey, including transfers, takes approximately 10h 47m.
Manchester to Lyon train services, operated by Avanti West Coast, depart from Manchester Piccadilly station.
Manchester to Lyon train services, operated by Avanti West Coast, arrive at Lyon Part Dieu station.
Book your Manchester to Lyon train tickets online with Avanti West Coast, Eurostar and 2 other operators.
The distance between Manchester and Lyon is 998.8 km. The road distance is 1,205 km.
You can take a train from Manchester Piccadilly to Lyon Part Dieu via London Euston, London St Pancras Intl, and Lille Europe in around 8h 46m.