The bus between Mainz and Messina takes 36h 40m. The bus runs, on average, 5 times per week from Mainz to Messina. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Mainz and Messina. The earliest departure is at 5:10 AM in the morning, and the last departure from Mainz is at 5:10 AM which arrives into Messina at 7:50 PM. All services require a transfer, and take on average 36h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Messina? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Messina. However, there are services departing from Mainz station and arriving at Messina station via Milan. The journey, including transfers, takes approximately 36h 40m.
Mainz to Messina bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Messina bus services, operated by FlixBus, arrive at Messina station.
Book your Mainz to Messina bus tickets online with FlixBus.
The distance between Mainz and Messina is 1,432.3 km. The road distance is 2,004 km.
You can take a bus from Mainz central train station to Messina via Milano, Autostazione Lampugnano in around 30h 20m.