There are 11 ways to get from Mainz to Messina by plane, train, ferry, bus, car, car ferry, or train (Trenitalia)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Catania–Fontanarossa Airport, train
best- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 6m€86–316Train, ferry
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Centraletrain S11
- Take the train from Milano Centrale to Villa S.Giovannitrain
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
22hBus
- Take the bus from Mainz central train station to Milanbus FlixBus 476
- Take the bus from Milano, Autostazione Lampugnano to Messinabus N597 / ...
30h 20m€102–236Drive, car ferry
- Drive from Mainz to Port of Salernocar
- Take the car ferry from Port of Salerno to Messinacarferry
22h 32m€261–395Fly Frankfurt to Palermo Airport, train
- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
- Take the train from Palermo Centrale to Messina Centraletrain
9h 56m€118–330Train, train to Stuttgart Airport, fly to Catania–Fontanarossa Airport
- Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain
- Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane STR - CTA
- Take the train from Catania Centrale to Messina Centraletrain
9h 38m€103–348Bus to Hahn, fly to Catania–Fontanarossa Airport, train
- Take the bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airportbus
- Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane HHN - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 53m€108–329Train to Cologne Bonn Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Catania–Fontanarossa Airport (CTA)plane CGN - CTA
- Take the train from Catania Centrale to Messina Centraletrain
10h 11m€94–331Train to Düsseldorf International Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Frankfurt to Düsseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Catania–Fontanarossa Airport (CTA)plane DUS - CTA
- Take the train from Catania Centrale to Messina Centraletrain
10h 8m€119–359Train
- Take the train from Frankfurt to Como S. Giovannitrain Ec
- Take the train from Como S.Giovanni to Milano Porta Garibalditrain S11
- Take the train from Milano P.Garibaldi to Messina Centraletrain
28h 21m€392–964Train, bus
- Take the train from Mainz Hbf to Zürich HBtrain
- Take the train from Zürich HB to Castione-Arbedotrain
- Take the train from Castione to Malpensa Aeroporto T2train S50
- Take the bus from Milan Malpensa Terminal 2 Arrivals to Messina Main Train Stationbus
33h 34m€194–356
Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) flights
Questions & Answers
The cheapest way to get from Mainz to Messina is to bus which costs €100 - €240 and takes 30h 20m.
The fastest way to get from Mainz to Messina is to fly and train which takes 8h 6m and costs €85 - €320.
No, there is no direct bus from Mainz station to Messina. However, there are services departing from Mainz central train station and arriving at Messina via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 30h 20m.
No, there is no direct train from Mainz to Messina. However, there are services departing from Mainz, Römisches Theater and arriving at Messina Centrale via Frankfurt, Como S.Giovanni and Milano P.Garibaldi. The journey, including transfers, takes approximately 28h 21m.
The distance between Mainz and Messina is 1617 km.
The best way to get from Mainz to Messina without a car is to train and ferry which takes 22h and costs .
It takes approximately 8h 6m to get from Mainz to Messina, including transfers.
Mainz to Messina bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Messina train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Frankfurt station.
The best way to get from Mainz to Messina is to bus which takes 30h 20m and costs €100 - €240. Alternatively, you can train, which costs €390 - €1000 and takes 28h 21m.
What companies run services between Mainz, Germany and Messina, Italy?
You can take a bus from Mainz central train station to Messina via Milano, Autostazione Lampugnano in around 30h 20m. Alternatively, you can take a train from Mainz, Römisches Theater to Messina Centrale via Frankfurt, Como S.Giovanni, and Milano P.Garibaldi in around 28h 21m.
- Website
- lufthansa.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €100–370
Flights from Frankfurt to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- €70–380
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €100–400
Flights from Frankfurt to Palermo Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €100–410
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- €100–400
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- €70–370
- Website
- ita-airways.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €100–370
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- €90–320
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- €85–250
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h 16m
- When
- Thursday, Tuesday, Sunday, Monday, Wednesday, and Friday
- Estimated price
- €75–230
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 5h 45m
- When
- Saturday
- Estimated price
- €100–370
- Website
- eurowings.com
Flights from Stuttgart Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 15m
- When
- Wednesday, Friday, Sunday, Monday, Tuesday, and Saturday
- Estimated price
- €75–230
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 35m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €75–220
Flights from Düsseldorf International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €80–210
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- €100–370
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Zurich
- Ave. Duration
- 5h 15m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €170–310
Flights from Düsseldorf International Airport to Catania–Fontanarossa Airport via Zurich
- Ave. Duration
- 5h 10m
- When
- Monday, Wednesday, Friday, and Sunday
- Estimated price
- €180–320
- Website
- ryanair.com
Flights from Hahn to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 25m
- When
- Tuesday, Friday, and Saturday
- Estimated price
- €50–200
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Bologna
- Ave. Duration
- 5h
- When
- Thursday
- Estimated price
- €60–180
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €11–19
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 52m
- Frequency
- Every 4 hours
- Estimated price
- €27–45
- Website
- https://www.trenitalia.com/en.html
Train from Milano P.Garibaldi to Messina Centrale
- Ave. Duration
- 17h 24m
- Frequency
- Once a week
- Estimated price
- €150–250
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 1h 27m
- Frequency
- Twice daily
- Estimated price
- €9–21
- Website
- https://www.trenitalia.com/en.html
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 58m
- Frequency
- Twice daily
- Estimated price
- €23–50
- Website
- https://www.trenitalia.com/en.html
- Phone
- +41 848 446 688
- Website
- sbb.ch
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €220–650
- Website
- https://www.sbb.ch/en
Train from Chiasso to Milano Centrale
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €18–55
- Website
- https://www.sbb.ch/en
Train from Frankfurt to Como S. Giovanni
- Ave. Duration
- 7h 2m
- Frequency
- 6 times a week
- Estimated price
- €230–650
- Website
- https://www.sbb.ch/en
Train from Como S.Giovanni to Milano Porta Garibaldi
- Ave. Duration
- 1h 2m
- Frequency
- Once daily
- Estimated price
- €17–50
- Website
- https://www.sbb.ch/en
- Phone
- +39 06 8937 1892
- Website
- italotreno.it
Train from Milano Centrale to Villa S.Giovanni
- Ave. Duration
- 10h 3m
- Frequency
- Once daily
- Estimated price
- €150–310
- Website
- https://www.italotreno.it/en
- Phone
- +49 30 311 682904
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- €12–35
- Website
- https://int.bahn.de/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 38 min
- Frequency
- Every 30 minutes
- Estimated price
- €19–55
- Website
- https://int.bahn.de/en
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 57 min
- Frequency
- Hourly
- Estimated price
- €26–70
- Website
- https://int.bahn.de/en
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €35–100
- Website
- https://int.bahn.de/en
- Phone
- +49 30 2970
- Website
- bahn.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- €14–22
- Website
- https://int.bahn.de/en
- Phone
- 0621 8301200
- Website
- suewex.de
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 54 min
- Frequency
- Every 4 hours
- Estimated price
- €14–20
- Schedules at
- suewex.de
- Phone
- +31 30 751 5155
- Website
- ns.nl
Train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhof
- Ave. Duration
- 1h 46m
- Frequency
- Once daily
- Estimated price
- €7–17
- Website
- https://www.ns.nl/en
Train from Mannheim, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 37 min
- Frequency
- Twice daily
- Estimated price
- €11–26
- Website
- https://www.ns.nl/en
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 39 min
- Frequency
- Every 4 hours
- Estimated price
- €15–35
- Website
- https://www.ns.nl/en
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 22m
- Frequency
- Every 3 hours
- Estimated price
- €22–50
- Website
- https://www.ns.nl/en
Train from Mainz Hbf to Zürich HB
- Ave. Duration
- 6h 22m
- Frequency
- Once daily
- Estimated price
- €50–120
- Website
- https://www.ns.nl/en
- Phone
- +32 70 79 79 79
- Website
- belgiantrain.be
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 49 min
- Frequency
- Twice a week
- Estimated price
- €26–55
- Website
- https://www.belgiantrain.be/en
- Phone
- +39 02 7249 4494
- my-link@trenord.it
- Website
- trenord.it
Train from Como S.Giovanni to Milano Porta Garibaldi
- Ave. Duration
- 1h 1m
- Frequency
- Every 30 minutes
- Estimated price
- €4–6
- Website
- https://www.trenord.it/en/
Train from Castione to Malpensa Aeroporto T2
- Ave. Duration
- 2h 12m
- Frequency
- Hourly
- Estimated price
- €8–10
- Website
- https://www.trenord.it/en/
- Phone
- +41 58 580 70 70
- Website
- sob.ch
Train from Zürich HB to Castione-Arbedo
- Ave. Duration
- 2h 50m
- Frequency
- Every 3 hours
- Estimated price
- €55–85
- Schedules at
- sob.ch
Rome2Rio's guide to FlixBus
Contact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- https://www.flixbus.fr
Bus from Mainz central train station to Milan
- Ave. Duration
- 12h 5m
- Frequency
- Once daily
- Estimated price
- €50–90
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Messina
- Ave. Duration
- 17h 15m
- Frequency
- Twice daily
- Estimated price
- €90–150
- Website
- https://www.flixbus.co.uk
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Milano, Autostazione Lampugnano to Messina
- Ave. Duration
- 18h 30m
- Frequency
- Twice daily
- Estimated price
- €75–150
- Website
- https://www.itabus.it/en/home
Bus from Milan Malpensa Terminal 2 Arrivals to Messina Main Train Station
- Ave. Duration
- 19h 25m
- Frequency
- Twice daily
- Estimated price
- €80–150
- Website
- https://www.itabus.it/en/home
- Phone
- (+39) 0923 98.11.20
- Website
- autoservizisalemi.it
Bus from Milano, Autostazione Lampugnano to Messina
- Ave. Duration
- 18h 40m
- Frequency
- 3 times a week
- Estimated price
- €50–75
- Schedules at
- autoservizisalemi.it
- info@flibco.com
- Website
- flibco.com
Bus from Mainz Short-term parking lot Am Schlag to Frankfurt Hahn Airport
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €17–35
- Website
- https://www.flibco.com/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39.090.57.37
- servizioclienti@carontetourist.it
- Website
- carontetourist.it
Car ferry from Port of Salerno to Messina
- Ave. Duration
- 9h
- Frequency
- Once daily
- Estimated price
- €29–60
- Schedules at
- carontetourist.it
- Passenger
- €29
- Cars
- €60
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More Questions & Answers
Mainz to Messina bus services, operated by FlixBus, arrive at Milan station.
Mainz to Messina train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Como S. Giovanni station.
Book your Mainz to Messina train tickets online with Omio.
Book your Mainz to Messina bus tickets online with Omio and FlixBus.
There are 1160+ hotels available in Messina.




































































