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How to get fromMainz to Messinaby plane, train, ferry, bus, car, or car ferry

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There are 11 ways to get from Mainz to Messina by plane, train, ferry, bus, car, or car ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Frankfurt to Catania–Fontanarossa Airport, train

    best
    1. Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane plane FRA - CTA
    2. Take the train from Catania Centrale to Messina Centraletrain train
    7h 46m
    €97–246

  2. Train, ferry

    1. Take the train from Frankfurt to Chiassotrain train Ec
    2. Take the train from Chiasso to Milano Centraletrain train S11
    3. Take the train from Milano Centrale to Villa S.Giovannitrain train Fr
    4. Take the ferry from Villa S.Giovanni to Messina Marittimaferry ferry V1 / ...
    19h 56m

  3. Bus via Offenbach

    1. Take the bus from Mühlheim am Main to Messina - Piazza della Repubblicabus bus
    26h 49m

  4. Drive, car ferry

    1. Drive from Mainz to Port of Salernocar car
    2. Take the carferry from Port of Salerno to Messinacarferry car ferry
    22h 32m
    €257–389

  5. Fly Frankfurt to Palermo Airport, train

    1. Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane plane FRA - PMO
    2. Take the train from Palermo Centrale to Messina Centraletrain train
    9h 25m
    €108–270

  6. Bus to Hahn, fly to Catania–Fontanarossa Airport, train

    1. Take the bus from Mainz, Hauptbahnhof to Hahnbus bus
    2. Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane plane HHN - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    8h 32m
    €110–280

  7. Train, train to Stuttgart Airport, fly to Catania–Fontanarossa Airport

    1. Take the train from Mainz, Hauptbahnhof to Mannheim, Hauptbahnhoftrain train
    2. Take the train from Mannheim, Hauptbahnhof to Hauptbahnhoftrain train
    3. Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane plane STR - CTA
    4. Take the train from Catania Centrale to Messina Centraletrain train
    9h 17m
    €105–392

  8. Train to Cologne Bonn Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Frankfurt to Siegburg Bftrain train
    2. Fly from Cologne Bonn Airport (CGN) to Catania–Fontanarossa Airport (CTA)plane plane CGN - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    9h 42m
    €105–439

  9. Train to Düsseldorf International Airport, fly to Catania–Fontanarossa Airport, train

    1. Take the train from Frankfurt to Düsseldorf Hbftrain train
    2. Fly from Düsseldorf International Airport (DUS) to Catania–Fontanarossa Airport (CTA)plane plane DUS - CTA
    3. Take the train from Catania Centrale to Messina Centraletrain train
    9h 49m
    €117–440

  10. Bus

    1. Take the bus from Wiesbaden Gartenfeldstraße P+R to Messina - Piazza della Repubblicabus bus
    32h 13m

  11. Bus via Foggia

    1. Take the bus from Frankfurt central train station to Foggiabus bus N422
    2. Take the bus from Foggia to Messinabus bus N596 / ...
    32h 49m
    €164–306

Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) flights

Calendar34Weekly Planes
Duration3h 52mAverage Duration
Ticket€64Cheapest Price
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Questions & Answers

Map of how to get from Mainz to Messina.ExpandLaunch map view
  • Distance: 1,617 km
  • Duration: 7h 46m

What companies run services between Mainz, Germany and Messina, Italy?

Onebus operates a bus from Mühlheim am Main to Messina - Piazza della Repubblica once a week, and the journey takes 22h 53m.

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