There are 11 ways to get from Mainz to Messina by plane, train, ferry, bus, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Catania–Fontanarossa Airport, train
best- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
- Take the train from Catania Centrale to Messina Centraletrain
7h 45m€96–256Train, ferry
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Centraletrain S11
- Take the train from Milano Centrale to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
19h 57mBus via Offenbach
- Take the bus from Mühlheim am Main to Messina - Piazza della Repubblicabus
24h 59m€223–311Drive, car ferry
- Drive from Mainz to Villa S. Giovannicar
- Take the carferry from Villa S. Giovanni to Tresmestiericarferry
18h 8m€325–478Bus to Hahn, fly to Catania–Fontanarossa Airport, train
- Take the bus from Mainz, Hauptbahnhof to Hahnbus
- Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane HHN - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 47m€146–355Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane STR - CTA
- Take the train from Catania Centrale to Messina Centraletrain
9h 29m€116–336Fly Frankfurt to Palermo Airport, train
- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
- Take the train from Palermo Centrale to Messina Centraletrain
9h 31m€111–279Train to Cologne Bonn Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Catania–Fontanarossa Airport (CTA)plane CGN - CTA
- Take the train from Catania Centrale to Messina Centraletrain
9h 34m€98–391Train to Düsseldorf International Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Frankfurt to Düsseldorf Hbftrain
- Fly from Düsseldorf International Airport (DUS) to Catania–Fontanarossa Airport (CTA)plane DUS - CTA
- Take the train from Catania Centrale to Messina Centraletrain
10h 10m€114–472Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Messina - Piazza della Repubblicabus
32h 6m€252–347Bus via Foggia
- Take the bus from Frankfurt central train station to Foggiabus N422
- Take the bus from Foggia to Messinabus 590
34h 33m€156–309
Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Mainz to Messina is to fly and train which costs €95 - €260 and takes 7h 45m.
The fastest way to get from Mainz to Messina is to fly and train which takes 7h 45m and costs €95 - €260.
No, there is no direct bus from Mainz to Messina. However, there are services departing from Mühlheim am Main and arriving at Messina - Piazza della Repubblica via . The journey, including transfers, takes approximately 24h 59m.
The distance between Mainz and Messina is 1617 km.
The best way to get from Mainz to Messina without a car is to train and ferry which takes 19h 57m and costs .
It takes approximately 7h 45m to get from Mainz to Messina, including transfers.
Mainz to Messina bus services, operated by Onebus, depart from Mühlheim am Main station.
Mainz to Messina bus services, operated by Onebus, arrive at Messina - Piazza della Repubblica station.
Book your Mainz to Messina bus tickets online with Omio.
There are 1163+ hotels available in Messina.
What companies run services between Mainz, Germany and Messina, Italy?
Onebus operates a bus from Mühlheim am Main to Messina - Piazza della Repubblica once a week. Tickets cost €210–290 and the journey takes 22h 53m.
- Website
- lufthansa.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 27m
- When
- Thursday, Saturday, Sunday, Monday, Wednesday, and Friday
- Estimated price
- €80–280
Flights from Frankfurt to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- €55–290
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 47m
- When
- Thursday to Wednesday
- Estimated price
- €60–310
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Thursday to Saturday
- Estimated price
- €85–300
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- €60–310
Flights from Düsseldorf International Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 36m
- When
- Thursday to Saturday
- Estimated price
- €65–700
- Website
- ita-airways.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 27m
- When
- Thursday, Saturday, Sunday, Monday, Wednesday, and Friday
- Estimated price
- €80–280
Flights from Frankfurt to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- €65–220
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 4h
- When
- Monday to Wednesday
- Estimated price
- €65–210
Flights from Frankfurt to Palermo Airport via Milan Linate
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- €95–200
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 5h 45m
- When
- Saturday
- Estimated price
- €85–300
Flights from Düsseldorf International Airport to Catania–Fontanarossa Airport via Milan Linate
- Ave. Duration
- 4h 10m
- When
- Monday to Friday
- Estimated price
- €75–240
- Website
- eurowings.com
Flights from Stuttgart Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 15m
- When
- Every day
- Estimated price
- €65–210
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- €95–350
Flights from Düsseldorf International Airport to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- €70–250
- Website
- ryanair.com
Flights from Hahn to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 35m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- €90–250
Flights from Hahn to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 5h 7m
- When
- Monday and Tuesday
- Estimated price
- €90–250
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Bologna
- Ave. Duration
- 5h
- When
- Monday to Thursday
- Estimated price
- €60–180
- Website
- swiss.com
Flights from Frankfurt to Palermo Airport via Zurich
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- €70–280
- Website
- lufthansa-city.com
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Monday to Thursday
- Estimated price
- €60–310
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Frankfurt to Chiasso
- Ave. Duration
- 6h 49m
- Frequency
- 6 times a week
- Estimated price
- €220–320
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Chiasso to Milano Centrale
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- €18–26
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Milano Centrale to Villa S.Giovanni
- Ave. Duration
- 8h 23m
- Frequency
- Every 4 hours
- Estimated price
- €160–280
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Milano Centrale to Villa S.Giovanni
- Ave. Duration
- 10h 27m
- Frequency
- Once daily
- Estimated price
- €140–230
- Website
- Italo Treno
- Phone
- +39 06 68475475
- Website
- Trenitalia Intercity
Train from Milano Centrale to Villa S.Giovanni
- Ave. Duration
- 15h 40m
- Frequency
- 3 times a week
- Estimated price
- €120–240
- Website
- Trenitalia Intercity
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 55m
- Frequency
- 4 times a day
- Estimated price
- €23–45
- Website
- Trenitalia Intercity
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Mainz, Hauptbahnhof to Hauptbahnhof
- Ave. Duration
- 1h 41m
- Frequency
- Every 4 hours
- Estimated price
- €30–70
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- €25–55
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- €35–80
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +31 30 751 5155
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 39 min
- Frequency
- Every 3 hours
- Estimated price
- €15–35
- Website
- Nederlandse Spoorwegen (NS)
Train from Frankfurt to Düsseldorf Hbf
- Ave. Duration
- 1h 23m
- Frequency
- Every 3 hours
- Estimated price
- €22–45
- Website
- Nederlandse Spoorwegen (NS)
- Phone
- +32 70 79 79 79
- Website
- Belgian Railways
Train from Frankfurt to Siegburg Bf
- Ave. Duration
- 51 min
- Frequency
- 3 times a week
- Estimated price
- €26–40
- Website
- Belgian Railways
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Mühlheim am Main to Messina - Piazza della Repubblica
- Ave. Duration
- 22h 53m
- Frequency
- Once a week
- Estimated price
- €210–290
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Messina - Piazza della Repubblica
- Ave. Duration
- 30h 46m
- Frequency
- Once a week
- Estimated price
- €250–340
- Website
- Onebus
- Phone
- +49 (0) 6543 5019-400
- reisebuero@bohr.de
- Website
- Bohr
Bus from Mainz, Hauptbahnhof to Hahn
- Ave. Duration
- 1h 15m
- Frequency
- Every 2 hours
- Estimated price
- €14–16
- Schedules at
- Bohr
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Frankfurt central train station to Foggia
- Ave. Duration
- 21h 15m
- Frequency
- Once daily
- Estimated price
- €120–200
- Website
- Flixbus
Bus from Foggia to Messina
- Ave. Duration
- 10h 40m
- Frequency
- Once daily
- Estimated price
- €50–85
- Website
- Flixbus
- Phone
- +39 06 88 93 82 32
- Website
- Itabus S.p.A.
Bus from Foggia to Messina
- Ave. Duration
- 9h 45m
- Frequency
- 4 times a week
- Estimated price
- €30–60
- Website
- Itabus S.p.A.
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
- Phone
- 090774409
- info@bluferries.it
- Website
- bluferries.it
Car ferry from Villa S. Giovanni to Tresmestieri
- Ave. Duration
- 25 min
- Frequency
- Hourly
- Estimated price
- €19–35
- Schedules at
- bluferries.it
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
Heading to Europe? Read this before you buy a Eurail Pass
Read the travel guide
Want to know more about Flixbus?
Read the travel guide












































