There are 10 ways to get from Mainz to Messina by plane, train, ferry, bus, car, or car ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Frankfurt to Catania–Fontanarossa Airport, train
best- Fly from Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA)plane FRA - CTA
- Take the train from Catania Centrale to Messina Centraletrain
7h 48m€92–243Train, ferry
- Take the train from Frankfurt to Chiassotrain Ec
- Take the train from Chiasso to Milano Centraletrain S11
- Take the train from Milano Centrale to Villa S.Giovannitrain Fr
- Take the ferry from Villa S.Giovanni to Messina Marittimaferry V1 / ...
19h 55mBus via Offenbach
- Take the bus from Mühlheim am Main to Messina - Piazza della Repubblicabus
25h 19m€214–297Drive, car ferry
- Drive from Mainz to Port of Salernocar
- Take the carferry from Port of Salerno to Messinacarferry
22h 33m€265–402Fly Frankfurt to Palermo Airport, train
- Fly from Frankfurt (FRA) to Palermo Airport (PMO)plane FRA - PMO
- Take the train from Palermo Centrale to Messina Centraletrain
9h 28m€104–274Train to Stuttgart Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Mainz, Hauptbahnhof to Hauptbahnhoftrain
- Fly from Stuttgart Airport (STR) to Catania–Fontanarossa Airport (CTA)plane STR - CTA
- Take the train from Catania Centrale to Messina Centraletrain
9h 27m€114–327Bus to Hahn, fly to Catania–Fontanarossa Airport, train
- Take the bus from Mainz, Hauptbahnhof to Hahnbus
- Fly from Hahn (HHN) to Catania–Fontanarossa Airport (CTA)plane HHN - CTA
- Take the train from Catania Centrale to Messina Centraletrain
8h 35m€114–357Train to Cologne Bonn Airport, fly to Catania–Fontanarossa Airport, train
- Take the train from Frankfurt to Siegburg Bftrain
- Fly from Cologne Bonn Airport (CGN) to Catania–Fontanarossa Airport (CTA)plane CGN - CTA
- Take the train from Catania Centrale to Messina Centraletrain
9h 27m€93–414Bus
- Take the bus from Wiesbaden Gartenfeldstraße P+R to Messina - Piazza della Repubblicabus
32h 13m€251–341Bus via Foggia
- Take the bus from Frankfurt central train station to Foggiabus N422
- Take the bus from Foggia to Messinabus 590
34h 33m€153–284
Frankfurt (FRA) to Catania–Fontanarossa Airport (CTA) flights
Comparing Your Travel Options
The cheapest way to get from Mainz to Messina is to fly and train which costs €90 - €250 and takes 7h 48m.
The fastest way to get from Mainz to Messina is to fly and train which takes 7h 48m and costs €90 - €250.
No, there is no direct bus from Mainz station to Messina. However, there are services departing from Mainz central train station and arriving at Messina - Piazza della Repubblica via Mühlheim am Main. The journey, including transfers, takes approximately 25h 19m.
The distance between Mainz and Messina is 1617 km.
The best way to get from Mainz to Messina without a car is to train and ferry which takes 19h 55m and costs .
It takes approximately 7h 48m to get from Mainz to Messina, including transfers.
Mainz to Messina bus services, operated by Onebus, depart from Mühlheim am Main station.
Mainz to Messina bus services, operated by Onebus, arrive at Messina - Piazza della Repubblica station.
Book your Mainz to Messina bus tickets online with Omio.
There are 1171+ hotels available in Messina.
What companies run services between Mainz, Germany and Messina, Italy?
Onebus operates a bus from Mühlheim am Main to Messina - Piazza della Repubblica once a week. Tickets cost €210–290 and the journey takes 22h 53m.
- Website
- lufthansa.com
Flights from Frankfurt to Catania–Fontanarossa Airport
- Ave. Duration
- 2h 30m
- When
- Every day
- Estimated price
- €85–300
Flights from Frankfurt to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- €60–320
Flights from Frankfurt to Palermo Airport
- Ave. Duration
- 2h 20m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €90–320
Flights from Frankfurt to Palermo Airport via Munich
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €90–320
Flights from Stuttgart Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- €60–330
Flights from Cologne Bonn Airport to Catania–Fontanarossa Airport via Munich
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- €65–330
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Palermo Centrale to Messina Centrale
- Ave. Duration
- 2h 54m
- Frequency
- Hourly
- Estimated price
- €26–40
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Catania Centrale to Messina Centrale
- Ave. Duration
- 2h 12m
- Frequency
- Every 30 minutes
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 0362 185 0590
- info@onebus.it
- Website
- Onebus
Bus from Mühlheim am Main to Messina - Piazza della Repubblica
- Ave. Duration
- 22h 53m
- Frequency
- Once a week
- Estimated price
- €210–290
- Website
- Onebus
Bus from Wiesbaden Gartenfeldstraße P+R to Messina - Piazza della Repubblica
- Ave. Duration
- 30h 53m
- Frequency
- Once a week
- Estimated price
- €250–340
- Website
- Onebus
- Phone
- +39.06.5210550
- Website
- Trenitalia
Ferry from Villa S.Giovanni to Messina Marittima
- Ave. Duration
- 20 min
- Frequency
- Hourly
- Website
- Trenitalia
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