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Mainz to Karlsruhe buses

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Trip Overview

The bus between Mainz and Karlsruhe takes 3h 50m. The bus runs, on average, 6 times per week from Mainz to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 50m
Duration
185 km
Distance
€18
Average price
6 times a week
Frequency

Mainz to Karlsruhe bus times

Buses run 6 times a week between Mainz and Karlsruhe. The earliest departure is at 5:10 AM in the morning, and the last departure from Mainz is at 5:10 AM which arrives into Karlsruhe at 9:00 AM. All services run direct with no transfers required, and take on average 3h 50m. The schedules shown below are for the next available departures.

Departing Wednesday, October 14, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Friday, October 16, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Saturday, October 17, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Sunday, October 18, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Monday, October 19, 2026

  •  → 

    bus bus 3h 50m • Direct

Departing Tuesday, October 20, 2026

  •  → 

    bus bus 3h 50m • Direct

Frequently asked questions

Want to know about travelling from Mainz to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Karlsruhe.ExpandLaunch map view
  • Distance: 184.7 km
  • Duration: 3h 50m

What companies run services between Mainz, Germany and Karlsruhe, Germany?

FlixBus operates a bus from Mainz central train station to Karlsruhe central train station twice daily. Tickets cost €15–24 and the journey takes 3h 50m.

Operators