The average bus between Madison and Des Moines takes 17h 26m and the fastest bus takes 12h 10m. The bus service runs several times per day from Madison to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Madison and Des Moines. The earliest departure is at 6:45 AM in the morning, and the last departure from Madison is at 5:55 PM which arrives into Des Moines at 2:35 PM. All services require a transfer, and take on average 17h 26m. The schedules shown below are for the next available departures.
Want to know about travelling from Madison to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madison to Des Moines. However, there are services departing from Madison station and arriving at Des Moines station via Chicago Bus Station station. The journey, including transfers, takes approximately 17h 26m.
Madison to Des Moines bus services, operated by Flixbus USA, depart from Madison station.
Madison to Des Moines bus services, operated by Flixbus USA, arrive at Des Moines station.
Book your Madison to Des Moines bus tickets online with Flixbus USA and Greyhound USA.
The distance between Madison and Des Moines is 382.6 km. The road distance is 780 km.
You can take a bus from Madison to Des Moines via Chicago Bus Station in around 10h 40m.