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Lowell to Hyannis buses

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Trip Overview

The bus between Lowell and Hyannis takes 2h 45m. The bus runs, on average, 5 times per week from Lowell to Hyannis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 45m
Duration
101 mi
Distance
$36
Average price
5 times a week
Frequency

Lowell to Hyannis bus times

Buses run 5 times a week between Lowell and Hyannis. The service departs Lowell at 7:50 PM in the evening, which arrives into Hyannis at 22:35:00. All services require a transfer at Boston and take an average of 2h 45m. The schedules shown below are for the next available departures.

Departing Thursday, October 22, 2026

  •  → 

    Greyhound USAPlymouth & Brockton2h 45m • 1 change

Departing Friday, October 23, 2026

  •  → 

    Greyhound USAPlymouth & Brockton2h 45m • 1 change

Departing Saturday, October 24, 2026

  •  → 

    Greyhound USAPlymouth & Brockton2h 45m • 1 change

Departing Sunday, October 25, 2026

  •  → 

    Greyhound USAPlymouth & Brockton2h 45m • 1 change

Departing Monday, October 26, 2026

  •  → 

    Greyhound USAPlymouth & Brockton2h 45m • 1 change

Frequently asked questions

Want to know about travelling from Lowell to Hyannis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Lowell to Hyannis.ExpandLaunch map view
  • Distance: 100.7 mi
  • Duration: 2h 45m

What companies run services between Lowell, MA, USA and Hyannis, MA, USA?

You can take a bus from Robert B Kennedy Bus Transfer Center to Hyannis Transportation Center via Boston and Boston South Buses in around 3h 17m.

Operators