The average bus between Louisville and Chicago takes 6h 37m and the fastest bus takes 6h. The bus service runs several times per day from Louisville to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Louisville and Chicago. The earliest departure is at 2:55 AM at night, and the last departure from Louisville is at 8:00 AM which arrives into Chicago at 2:15 PM. All services run direct with no transfers required, and take on average 6h 37m. The schedules shown below are for the next available departures.
Want to know about travelling from Louisville to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Louisville station and arriving at Chicago station. Services depart twice daily, and operate Once daily. The journey takes approximately 6h 37m.
Louisville to Chicago bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
Louisville to Chicago bus services, operated by Amtrak Thruway, arrive at Chicago Union Station.
Book your Louisville to Chicago bus tickets online with Amtrak Thruway.
The distance between Louisville and Chicago is 432.9 km. The road distance is 481 km.
Amtrak Thruway operates a bus from Louisville, KY to Chicago Union Station twice daily. Tickets cost $50–60 and the journey takes 6h.