- Distance: 298.5 mi
- Duration: 6h 34m
The average bus between Louisville and Chicago takes 6h 34m and the fastest bus takes 5h 10m. The bus service runs several times per day from Louisville to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Louisville and Chicago. The earliest departure is at 3:00 AM at night, and the last departure from Louisville is at 8:00 PM which arrives into Chicago at 12:10 AM. All services run direct with no transfers required, and take on average 6h 34m. The schedules shown below are for the next available departures.
Want to know about travelling from Louisville to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Louisville station and arriving at Chicago station. Services depart every 4 hours, and operate 4 times a day. The journey takes approximately 6h 34m.
Louisville to Chicago bus services, operated by Flixbus USA, depart from Louisville Bus Station.
Louisville to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Book your Louisville to Chicago bus tickets online with Flixbus USA and Greyhound USA.
The distance between Louisville and Chicago is 432.9 km. The road distance is 480 km.
Greyhound USA operates a bus from Louisville Bus Station to Chicago Bus Station 4 times a day. Tickets cost $45–90 and the journey takes 6h. Three other operators also service this route.
