There are 8 ways to get from Indianapolis to Missouri by plane, bus (Greyhound), bus, train, car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Indianapolis to Kansas City
best- Fly from Indianapolis (IND) to Kansas City (MCI)plane IND - MCI
4h 56m$222–552Bus (Greyhound)
cheapest- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus Greyhound US0421
- Take the bus from St Louis Bus Station to Kansas City Bus Stationbus Greyhound US1200 / ...
9h 25m$64–116Bus, train
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus Greyhound US0421
- Take the train from St. Louis to Kansas Citytrain Missouri River Runner / ...
10h 47m$69–231Drive 481.9 mi
- Drive from Indianapolis to Kansas Citycar 481.9 mi
8h 7m$88–127Fly Indianapolis to Columbia Regional Airport
- Fly from Indianapolis (IND) to Columbia Regional Airport (COU)plane IND - COU
5h 43m$112–447Fly Indianapolis to Springfield-Branson National Airport
- Fly from Indianapolis (IND) to Springfield-Branson National Airport (SGF)plane IND - SGF
6h 13m$158–822Bus to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
- Take the bus from Indianapolis to Chicagobus
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
7h 11m$129–849Train (Amtrak)
- Take the train from Indianapolis to Chicago Union Stationtrain Cardinal
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
13h 35m$100–209
Indianapolis to Missouri by bus (Greyhound)
Questions & Answers
The cheapest way to get from Indianapolis to Missouri is to bus which costs $60 - $120 and takes 9h 25m.
The fastest way to get from Indianapolis to Missouri is to fly which takes 4h 56m and costs $220 - $550.
No, there is no direct bus from Indianapolis station to Missouri station. However, there are services departing from Indianapolis Union Station and arriving at Kansas City Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 9h 25m.
No, there is no direct train from Indianapolis to Missouri. However, there are services departing from Indianapolis and arriving at Metro Center via Chicago Union Station and Union Station. The journey, including transfers, takes approximately 13h 35m.
The distance between Indianapolis and Missouri is 492 miles. The road distance is 484.7 miles.
The best way to get from Indianapolis to Missouri without a car is to bus which takes 9h 25m and costs $60 - $120.
It takes approximately 4h 56m to get from Indianapolis to Missouri, including transfers.
Indianapolis to Missouri bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indianapolis to Missouri train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Missouri is to fly which takes 4h 56m and costs $220 - $550. Alternatively, you can bus, which costs $60 - $120 and takes 9h 25m, you could also train, which costs $95 - $210 and takes 13h 35m.
What companies run services between Indianapolis, IN, USA and Missouri, USA?
Southwest Airlines flies from Indianapolis (IND) to Kansas City (MCI) 4 times a day. Alternatively, you can take a bus from Indianapolis Union Station to Kansas City Bus Station via St Louis Bus Station in around 9h 25m.
- Website
- southwest.com
Flights from Indianapolis to Kansas City
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $85–550
Flights from Indianapolis to Kansas City via Chicago Midway International Airport
- Ave. Duration
- 3h 38m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $95–600
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $100–750
- Website
- aa.com
Flights from Indianapolis to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $60–380
Flights from Indianapolis to Columbia Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $110–550
Flights from Indianapolis to Columbia Regional Airport via Charlotte
- Ave. Duration
- 6h 5m
- When
- Tuesday
- Estimated price
- $100–500
Flights from Indianapolis to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $140–800
Flights from Indianapolis to Springfield-Branson National Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Indianapolis to Springfield-Branson National Airport via Charlotte
- Ave. Duration
- 6h 39m
- When
- Every day
- Estimated price
- $210–1,000
- Website
- united.com
Flights from Indianapolis to Columbia Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $60–380
Flights from Indianapolis to Springfield-Branson National Airport via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $140–800
Flights from Indianapolis to Springfield-Branson National Airport via Houston
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Indianapolis to Springfield-Branson National Airport via Denver
- Ave. Duration
- 8h 29m
- When
- Every day
- Estimated price
- $270–1,200
- Website
- delta.com
Flights from Indianapolis to Springfield-Branson National Airport via Atlanta
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $190–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $35–180
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $30–60
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $65–150
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $30–55
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- 4 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Indianapolis to Chicago
- Ave. Duration
- 3h 15m
- Frequency
- 4 times a day
- Estimated price
- $22–90
- Schedules at
- flixbus.com
- Adult
- $22–90
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Indianapolis to Missouri bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Missouri is 1h behind Indianapolis. It is currently 8:57 PM in Indianapolis and 7:57 PM in Missouri.
Indianapolis to Missouri train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Indianapolis to Missouri is 485 miles. It takes approximately 8h 7m to drive from Indianapolis to Missouri.
Book your Indianapolis to Missouri bus tickets online with Omio and FlixBus.
There are 333+ hotels available in Missouri.